AI Article Synopsis
- * The researchers found that 86.7% of the rabbits developed left pulmonary hypertension within 1-3 months post-surgery, with all exhibiting the condition by three months after the operation.
- * The study observed that left pulmonary arterial pressure was consistently higher than that of the right, along with significant pathological changes in the left pulmonary arterioles compared to the right.
Article Abstract
This article presents a new rabbit model of pulmonary hypertension using rabbits. The left pulmonary artery of the rabbits was anastomosed on the descending aorta side-to-side and the proximal left pulmonary was banded. A portion of the arteries in the left upper lobe was ligated, and the majority of shunted blood was driven to the left middle and lower lobe. The left pulmonary hypertension was established in 86.7% of the rabbits within 1-3 months post operation and the left pulmonary hypertension was formed in all rabbits after 3 months post operation with pathological changes of pulmonary arteriole. The left pulmonary arterial pressure was higher than right pulmonary arterial pressure and the pathological changes were less evident in the right pulmonary arteriole.
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| http://dx.doi.org/10.1016/s0967-2109(01)00124-7 | DOI Listing |
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