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Acute Rhinosinusitis: Rapid Evidence Review.
Am Fam Physician
January 2025
University of Kansas Medical Center, Kansas City.
Acute rhinosinusitis causes more than 30 million patients to seek health care per year in the United States. Respiratory tract infections, including bronchitis and sinusitis, account for 75% of outpatient antibiotic prescriptions in primary care. Sinusitis is a clinical diagnosis; the challenge lies in distinguishing between the symptoms of bacterial and viral sinusitis.
View Article and Find Full Text PDFDysuria: Evaluation and Differential Diagnosis in Adults.
Am Fam Physician
January 2025
Martin Army Community Hospital, Fort Moore, Georgia.
Dysuria, a feeling of pain or discomfort during urination, is often caused by urinary tract infection but can also be due to sexually transmitted infection, bladder irritants, skin lesions, and some chronic pain conditions. History is most often useful for finding signs of sexually transmitted infection, complicated infections, lower urinary symptoms in males, and noninfectious causes. Most patients presenting with dysuria should have a urinalysis performed.
View Article and Find Full Text PDFInherent differential microbial assemblages and functions associated with corals exhibiting different thermal phenotypes.
Sci Adv
January 2025
Division of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Certain coral individuals exhibit enhanced resistance to thermal bleaching, yet the specific microbial assemblages and their roles in these phenotypes remain unclear. We compared the microbial communities of thermal bleaching-resistant (TBR) and thermal bleaching-sensitive (TBS) corals using metabarcoding and metagenomics. Our multidomain approach revealed stable distinct microbial compositions between thermal phenotypes.
View Article and Find Full Text PDFCan nCD64 and mCD169 biomarkers improve the diagnosis of viral and bacterial respiratory syndromes in the emergency department? A prospective cohort pilot study.
Infection
January 2025
Department of Medicine (DMED), University of Udine, Udine, Italy.
Purpose: Differentiating infectious from non-infectious respiratory syndromes is critical in emergency settings. This study aimed to assess whether nCD64 and mCD169 exhibit specific distributions in patients with respiratory infections (viral, bacterial, or co-infections) and to evaluate their diagnostic accuracy compared to non-infectious conditions.
Methods: A prospective cohort study enrolled 443 consecutive emergency department patients with respiratory syndromes, categorized into four groups: no infection group (NOIG), bacterial infection group (BIG), viral infection group (VIG), and co-infection group (COING).
A recurrence model for non-puerperal mastitis patients based on machine learning.
PLoS One
January 2025
Department of Laboratory Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Objective: Non-puerperal mastitis (NPM) is an inflammatory breast disease affecting women during non-lactation periods, and it is prone to relapse after being cured. Accurate prediction of its recurrence is crucial for personalized adjuvant therapy, and pathological examination is the primary basis for the classification, diagnosis, and confirmation of non-puerperal mastitis. Currently, there is a lack of recurrence models for non-puerperal mastitis.
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