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Monkeypox and chickenpox co-infection in a person living with Human Immunodeficiency Virus.
J Infect Dev Ctries
July 2024
Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Nigeria.
Introduction: The 2022 mpox global outbreak underscores the need for an improved understanding of mpox epidemiology, co-morbidities, and clinical management/outcome. We report a case of a 30-year-old Nigerian antiretroviral treatment-experienced person living with human immunodeficiency virus (PLHIV) who had PCR-confirmed mpox and chickenpox co-infection.
Case Presentation: The patient presented with a generalized itchy rash of three weeks and antecedent low-grade fever.
Efficacy, reactogenicity, and safety of the adjuvanted recombinant zoster vaccine for the prevention of herpes zoster in Chinese adults ≥ 50 years: A randomized, placebo-controlled trial.
Hum Vaccin Immunother
December 2024
GSK, Rockville, MD, USA.
Phase III multi-country studies (ZOE-50/70) demonstrated that the adjuvanted recombinant zoster vaccine (RZV) was well tolerated and prevented herpes zoster (HZ) in healthy ≥ 50-year-olds, with a vaccine efficacy (VE) > 90% across age groups. These pivotal trials did not enroll participants from mainland China where RZV is licensed, therefore similar clinical data are missing for this population. In this phase IV observer-blind study (NCT04869982) conducted between 2021 and 2023 in China, immunocompetent and medically stable ≥ 50-year-olds were randomized 1:1 to receive two RZV or placebo doses, 2 months apart.
View Article and Find Full Text PDFInfectious diseases in Poland in 2021.
Przegl Epidemiol
May 2024
Zakład Epidemiologii Chorób Zakaźnych i Nadzoru, Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy, Polska.
OBJECTIVE OF THE WORK. As 2021 was the second year of COVID-19 pandemic we expect the continuous impact of the pandemic on other infectious diseases. We aimed at reviewing the national infectious surveillance data based on available surveillance reports (Epidemiological Chronicle) to summarize the infectious disease situation in 2021.
View Article and Find Full Text PDFUK healthcare professionals' attitudes towards the introduction of varicella vaccine into the routine childhood vaccination schedule and their preferences for administration.
Vaccine
April 2024
Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Background: Varicella (chickenpox) is a highly contagious disease caused by the varicella-zoster virus. Although typically mild, varicella can cause complications leading to severe illness and even death. Safe and effective varicella vaccines are available.
View Article and Find Full Text PDFBurden of chickenpox complications in Poland, 2006 to 2021: A comprehensive registry-based study.
Euro Surveill
February 2024
NHS National Services Scotland, Digital and Security, Edinburgh, United Kingdom.
BackgroundChickenpox, a vaccine-preventable disease caused by the varicella zoster virus, generally presents with mild symptoms but can cause complications necessitating hospitalisation. In Poland, since 2009, vaccination has been obligatory for children up to 12 years of age who are particularly vulnerable to infection and for children in their vicinity.AimTo examine the burden of chickenpox complications and the trends of hospitalisation arising from these complications over time in the Polish population.
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