Objective: To determine the prevalence of bacterial vaginosis among family planning users and the relationship between clinical symptoms and gynecologic signs.
Material And Methods: Four hundred and fifty women were studied: they answered a detailed structured questionnaire and had a vaginal secretion sampling to make the diagnose of bacterial vaginosis according to the Amsel et al criteria.
Results: 85 women were excluded because they were found to have either yeast or trichomonas. 144/450 women were found to have bacterial vaginosis (32%), while 221 women without evidence of this problem served as a comparison group. We found an increased number of sexual partners, and more abortions and premature rupture of membranes in women with bacterial vaginosis than women without the problem. More than 50% of patients with bacterial vaginosis were asymptomatic of disease complaints and the only sign with significance observed in bacterial vaginosis patients was a grey vaginal discharge. Use of IUD wasn't associated with bacterial vaginosis.
Conclusions: The prevalence of bacterial vaginosis we found in a family planning clinic was similar to those that have been reported in developed countries whereas it seems to be higher than other national studies. We must emphasize the importance of an accurate diagnose and a suitable treatment to prevent subsequent complications.
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Pak J Med Sci
January 2025
Asiya Fayyaz Department of Obstetrics and Gynecology, Nishtar Hospital, Multan, Pakistan.
Objective: To compare the efficacy of a probiotic plus antibiotic with antibiotic therapy alone for the prevention of the recurrence of bacterial vaginosis.
Method: A Randomized control trial was conducted in the Gynecological Department of Nishtar Hospital, Multan, between July 2022 and June 2023. One hundred and twenty (N=120) women with bacterial vaginosis, all cured with metronidazole, were enrolled and randomized.
Int J Nanomedicine
January 2025
Department of Mechanical Engineering, Chang Gung University, Taoyuan, 33302, Taiwan.
Background: In clinical practice, imiquimod is used to treat Human Papillomavirus (HPV)-related lesions, such as condyloma and Cervical Intraepithelial Neoplasia (CIN). Metronidazole is the most commonly prescribed antibiotic for bacterial vaginosis. The study developed biodegradable imiquimod- and metronidazole-loaded nanofibrous mats and assessed their effectiveness for the topical treatment of cervical cancer, a type of HPV-related lesion.
View Article and Find Full Text PDFIntroduction Bacterial vaginosis (BV) is a risk factor for preterm delivery. Yet, previous studies have found BV treatment ineffective in preventing preterm delivery in unselected population. This study aims to evaluate the effectiveness of BV screening and treatment in reducing the rate of preterm deliveries before 37 weeks in high-risk women.
View Article and Find Full Text PDFPLoS One
January 2025
McMaster Immunology Research Centre and Department of Medicine, McMaster University, Hamilton, ON, Canada.
Background: A dysbiotic vaginal microbiome (VMB) is associated with clinical conditions such as bacterial vaginosis (BV) and an increased risk of human immunodeficiency virus (HIV-1) infection. Considering the high prevalence of BV among African, Caribbean and Black (ACB) women, we conducted a prospective, randomized, open-label phase 1 clinical trial to determine the feasibility, safety and tolerability of administering low-dose estrogen, probiotics or both in combination to improve vaginal health and decrease HIV-1 susceptibility.
Methods: ACB women aged 18-49 from the Greater Toronto Area (GTA) were randomized to one of four study arms: intravaginal estradiol (Estring©; 7.
BMC Pregnancy Childbirth
January 2025
Department of Social Administration & Justice, Faculty of Arts & Social Sciences, Universiti Malaya, Kuala Lumpur, Asbah, Razali, 50603, Malaysia.
Introduction: Bacterial vaginosis (BV) is one of the most common genital tract infections among women of reproductive age. The existence of BV among pregnant women has momentously attracted the attention of both clinicians and the scientific community due to its potential link with adverse clinical outcomes in pregnancy.
Methods: To evaluate the prevalence, risk factors, and adverse outcomes of bacterial vaginosis among pregnant women, a comprehensive systematic review was conducted based on the preferred reporting items for systematic review and meta-analyses (PRISMA) criteria.
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