Background: We aimed to determine if an association exists between uncomplicated hepatitis C virus (HCV) infection and depression or fatigue.
Method: A review of the literature was undertaken.
Results: There is an association between HCV infection and either depression or fatigue in certain circumstances--those who are aware they are HCV positive, those with advanced liver disease and those seen in specialist referral centres. All these studies are subject to important biases. There are only a few studies in which knowledge of HCV status and assessment of fatigue or depression is independent. These studies do not suggest an association. There is no association between conventional markers of liver disease and depression or fatigue.
Conclusions: Despite anecdotal evidence to the contrary, at the moment there is no evidence that HCV infection per se is associated with fatigue or depression, and there is a suggestion that it is not. The same risk factors that exist for fatigue in other physical illnesses, such as metabolic disorder, mood disorder, demographics and lack of exercise, certainly exist for HCV. Although there are elegant theoretical mechanisms, there is no compelling epidemiological evidence for an additional HCV specific fatigue or depression factor.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1017/s0033291701004615 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Meta-narrative review: the impact of music therapy on sleep and future research directions.
Front Neurol
January 2025
Art Healing and Cognitive Science Research Center, Department of Music, School of Arts and Design, Yanshan University, Qinhuangdao, China.
Sleep is essential to human health, yet 27% of the global population suffers from sleep issues, which often lead to fatigue, depression, and impaired cognitive function. While pharmacological treatments exist, non-pharmacological approaches like music therapy have shown promise in enhancing sleep quality. This review, analyzing 27 studies with various experimental paradigms, confirms that music therapy significantly improves subjective sleep quality, largely by alleviating anxiety and regulating mood through perceptual pathways.
View Article and Find Full Text PDFAssociation of high complement and low immunoglobulins with the clinical symptoms of patients with fibromyalgia.
Biopsychosoc Med
January 2025
Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashiku, Fukuoka, 812-8582, Japan.
Background: Fibromyalgia (FM) is a disease characterized by chronic widespread pain concomitant with various symptoms such as fatigue and anxiety. Although chronic inflammation has been implicated in the immunological abnormalities of FM, there are few human studies on complement and immunoglobulins. In this study, we investigated the immunological characteristics of FM patients and the association between their clinical symptoms and immunological indices, including complement and immunoglobulins.
View Article and Find Full Text PDFBackground: Critical care nurses are vulnerable to depression, which not only lead to poor well-being and increased turnover intention, but also affect their working performances and organizational productivity as well. Work related factors are important drivers of depressive symptoms. However, the non-liner and multi-directional relationships between job demands-resources and depressive symptoms in critical care nurses has not been adequately analyzed.
View Article and Find Full Text PDFHigh fatigue levels among psychiatric outpatients - the validity of the Danish Patient Reported Outcomes Measurement Information System Fatigue Short-Form (PROMISF-SF).
J Patient Rep Outcomes
January 2025
Department of Clinical Medicine, Faculty of Health, University of Copenhagen, Copenhagen, Denmark.
Background: Patient Reported Outcomes Measurement Information System Fatigue Short-Form (PROMIS-F-SF) is a self-administered, patient reported outcome (PRO) designed to assess fatigue in healthy and clinical populations and for tracking progress during treatment for disorders complicated with fatigue.
Methods: Patients in the Mental Health Service Outpatient Clinics and healthy volunteers were invited to complete a survey, which included the Danish translation of the PROMIS-F-SF, the Chalder Fatigue Scale (CFS-11), and measures of depression and anxiety. We conducted a confirmatory factor analysis of the previously suggested single-factor structure of the instrument.
Factors Associated with the Breastfeeding Aversion Response.
Breastfeed Med
January 2025
Faculty of Health Sciences, Nursing Department, Bilecik Seyh Edebali University, Bilecik, Turkey.
The breastfeeding aversion response (BAR) is defined as the compulsion to remove the baby from the breast in response to negative physical sensations experienced during breastfeeding. This phenomenon is characterized by involuntary and overwhelming feelings of disgust that arise during breastfeeding or at various stages of the breastfeeding process. The aim of the study is to evaluate the frequency of BAR and affecting factors in mothers with breastfeeding experience in Türkiye.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!