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Signal Transduction of Constitutive Activating and Inactivating Eel Lutropin/Choriogonadotropin Receptor (Eel LH/CGR) Mutants by Recombinant Equine Chorionic Gonadotropin (Rec-eCG).
Dev Reprod
December 2024
Carbon-Neutral Resources Research Center, Institute of Genetic Engineering, Hankyong National University, Anseong 17579, Korea.
Lutropin/choriogonadotropin receptor (LH/CGR) is a member of the G protein-coupled receptor superfamily. LH/CGRs in fish and mammalian species have been reported to contain naturally occurring, constitutively activating, and inactivating mutations in highly conserved regions. The present study was designed to determine the functional aspect of eel LH/CGR signal transduction.
View Article and Find Full Text PDFUpscaling a regional telecardiology service to a nationwide coverage and beyond: the experience of the Telehealth Network of Minas Gerais.
BMJ Glob Health
January 2025
Departament of Internal Medicine, Medical School, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Cardiovascular diseases are the leading cause of death globally and in Brazil. The provision of quality healthcare faces challenges due to resource scarcity and unequal distribution, particularly affecting rural areas. Telehealth strategies have shown potential to address these challenges by improving access to specialised care.
View Article and Find Full Text PDFMyocarditis as a Possible Underlying Cause for Mid-Ventricular Takotsubo Cardiomyopathy: A Case Report.
Cureus
December 2024
Medicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Our case report characterizes a rare presentation of mid-ventricular Takotsubo cardiomyopathy (TTC) in a patient with suspected myocarditis as an underlying cause. Mid-ventricular TTC is a rare variant of TTC presenting with overlapping symptoms and physical exam findings of acute coronary syndrome, which often leads to misdiagnosis as myocardial infarction. Our case is of a 77-year-old female patient with a history of hyperlipidemia, right breast ductal carcinoma in situ, and diverticular disease who presented to the emergency department for evaluation of chest pain radiating to the jaw with associated nausea and vomiting.
View Article and Find Full Text PDFECGEFNet: A two-branch deep learning model for calculating left ventricular ejection fraction using electrocardiogram.
Artif Intell Med
February 2025
Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, China; Clinical Medical Research Center of Imaging in Liaoning Province, Shenyang, China.
Left ventricular systolic dysfunction (LVSD) and its severity are correlated with the prognosis of cardiovascular diseases. Early detection and monitoring of LVSD are of utmost importance. Left ventricular ejection fraction (LVEF) is an essential indicator for evaluating left ventricular function in clinical practice, the current echocardiography-based evaluation method is not avaliable in primary care and difficult to achieve real-time monitoring capabilities for cardiac dysfunction.
View Article and Find Full Text PDFDevelopment and validation of a novel coronary artery disease risk prediction model.
J Transl Med
January 2025
Department of Cardiology, The 904th Hospital of the PLA Joint Logistics Support Force, Wuxi, Jiangsu, 214044, People's Republic of China.
Objective: This study aims to develop a novel risk assessment tool for coronary artery disease (CAD) based on data of patients with chest pain in outpatient and emergency department, thereby facilitating the effective identification and management of high-risk patients.
Methods: A retrospective analysis was conducted on patients hospitalized for chest pain. Patients were divided into a control group and a CAD group based on angiographic results.
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