Many real-world medical applications require timely actions to be taken in time pressured situations. Existing approaches to dynamic decision modeling have provided relatively efficient methods for representing and reasoning, but the process of computing the optimal solution has remained intractable. A major reason for this difficulty is the lack of models that are capable of modeling temporal processes and dealing with time-critical situations. This paper presents a formalism called the time-critical dynamic influence diagram that provide the capability for both temporal and space abstraction. To deal with the time criticality, we exploit the concept of space and temporal abstraction to reduce the computational complexity and propose an anytime algorithm for the solution process. We illustrate through out the paper, the various approaches with the use of a medical problem on the treatment of cardiac arrest.
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http://dx.doi.org/10.1016/s0010-4825(01)00036-1 | DOI Listing |
Neurosci Biobehav Rev
December 2024
Centre for Eudaimonia and Human Flourishing, Linacre College, University of Oxford, Oxford, UK; Department of Psychiatry, University of Oxford, Oxford, UK; Center for Music in the Brain, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address:
Turbulence is a universal principle for fast energy and information transfer. Moving beyond the turbulence of fluid dynamics, turbulence has recently been demonstrated in brain dynamics. Importantly, turbulence can be expressed as the rich variability across spacetime of the local levels of synchronisation of coupled brain signals.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2024
Department of Mechanical Engineering, University of Sheffield, Sheffield, United Kingdom.
Cell-based therapies represent the current frontier of biomedical innovations, with the technologies required underpinning treatments as broad as CAR-T cell therapies, stem cell treatments, genetic therapies and mRNA manufacture. A key bottleneck in the manufacturing process for each of these lies in the expansion of cells within a bioreactor vessel, requiring by far the greatest share of time for what are often time-critical therapies. While various designs, culture feeding and mixing methods are employed in these bioreactors, a common concern among manufacturers and researchers lies in whether shear stresses generated by culture media flow will damage cells and inhibit expansion.
View Article and Find Full Text PDFData visualization recommendation aims to assist the user in creating visualizations from a given dataset. The process of creating appropriate visualizations requires expert knowledge of the available data model as well as the dashboard application that is used. To relieve the user from requiring this knowledge and from the manual process of creating numerous visualizations or dashboards, we present a context-aware visualization recommender system (VisCARS) for monitoring applications that automatically recommends a personalized dashboard to the user, based on the system they are monitoring and the task they are trying to achieve.
View Article and Find Full Text PDFResusc Plus
June 2024
University Hospital Würzburg, Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Oberdürrbacher Straße 6, 97080 Würzburg, Germany.
Background: Handovers during medical emergencies are challenging due to time-critical, dynamic and oftentimes unorderly and distracting situations. We evaluated the effect of distraction-reduced clinical surroundings during handover on (1) the recall of handover information, (2) the recall of information from the surroundings and (3) self-reported workload in a simulated in-hospital cardiac arrest scenario.
Methods: In a parallel group design, emergency team leaders were randomly assigned to receive a structured handover of a cardio-pulmonary resuscitation (CPR) either inside the room ("inside group") right next to the ongoing CPR or in front of the room ("outside group") with no audio-visual distractions from the ongoing CPR.
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