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Diagnostic challenges in pediatric Cushing's disease associated with chronic renal failure: a report of three patients.
J Pediatr Endocrinol Metab
November 2024
Department of Endocrinology, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina.
Article Synopsis
- Cushing's disease (CD) co-occurring with chronic kidney disease (CKD) is rare and makes diagnosis challenging due to CKD-induced hypercortisolism; this report presents three female cases to improve understanding of diagnosis in such contexts.
- Each patient, aged between 12 and 16, had various CKD-related conditions and presented symptoms typical of CD, which were confirmed through clinical and biochemical evaluations; surgical interventions led to remission, but some patients developed pituitary deficiencies.
- These cases highlight the need for careful clinical assessment in diagnosing CD among CKD patients, as clear diagnostic criteria are currently lacking.
Feasibility of Early Surgical Treatment for Adolescent Patients with Prolactinoma: A Case Report and Literature Review.
Medicina (Kaunas)
August 2024
Department of Neurosurgery, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.
Article Synopsis
- * A case study of a 14-year-old girl highlighted the challenges of diagnosing prolactinomas, as her symptoms were initially mistaken for normal developmental changes, but later evaluations showed a significant pituitary mass.
- * Early surgical treatment successfully normalized prolactin levels and triggered normal puberty in the patient, emphasizing that adolescents with aggressive tumors may benefit from prompt surgery instead of relying solely on medication.
Diagnosis and Dental Management of a Patient With Forbes Albright Syndrome: A Report of a Rare Case.
Cureus
June 2024
Department of Conservative Dentistry and Endodontics and Endodontics, Kalinga Institute of Dental Sciences, KIIT (Deemed to be University), Bhubaneswar, IND.
Forbes Albright syndrome is a hyperprolactinemia syndrome linked to a pituitary tumor associated with galactorrhea and amenorrhea. Cabergoline, an ergot derivative, is its drug of choice. Here, we report the oral manifestations and management of a case of a 32-year-old female, diagnosed and treated with the same.
View Article and Find Full Text PDFMayer-Rokitansky-Kuster-Hauser Syndrome Presented with Diabetes Mellitus and Primary Amenorrhea: A Case Report.
Mymensingh Med J
July 2024
Dr Mamun Ur Rashid, DEM (Course), Department of Endocrinology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:
Article Synopsis
- MRKH syndrome is a rare condition that leads to the absence or underdevelopment of the uterus and vagina in females, affecting their reproductive health.
- A 17-year-old girl with MRKH was admitted for primary amenorrhea and poorly controlled diabetes, despite having normal growth and no significant medical or family history.
- Clinical evaluations revealed normal external genitalia, a blind vaginal pouch, absence of the uterus and cervix, and an ectopic left kidney, while her blood glucose levels remained poorly managed.
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