Several planetary missions have reported the presence of substantial numbers of energetic ions and electrons surrounding Jupiter; relativistic electrons are observable up to several astronomical units (au) from the planet. A population of energetic (>30[?]keV) neutral particles also has been reported, but the instrumentation was not able to determine the mass or charge state of the particles, which were subsequently labelled energetic neutral atoms. Although images showing the presence of the trace element sodium were obtained, the source and identity of the neutral atoms---and their overall significance relative to the loss of charged particles from Jupiter's magnetosphere---were unknown. Here we report the discovery by the Cassini spacecraft of a fast (>103[?]km[?]s-1) and hot magnetospheric neutral wind extending more than 0.5[?]au from Jupiter, and the presence of energetic neutral atoms (both hot and cold) that have been accelerated by the electric field in the solar wind. We suggest that these atoms originate in volcanic gases from Io, undergo significant evolution through various electromagnetic interactions, escape Jupiter's magnetosphere and then populate the environment around the planet. Thus a 'nebula' is created that extends outwards over hundreds of jovian radii.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1038/415994a | DOI Listing |
Chaos
December 2024
Departament de Matemàtiques, Universitat Politècnica de Catalunya, Av. Diagonal 647, 08028 Barcelona, Spain.
The Hilda group is a set of asteroids whose mean motion is in a 3:2 orbital resonance with Jupiter. In this paper, we use the planar Circular Restricted Three-Body Problem (CRTBP) as a dynamical model and we show that there exists a family of stable periodic orbits that are surrounded by islands of quasi-periodic motions. We have computed the frequencies of these quasi-periodic motions and we have shown how the Hilda family fits inside these islands.
View Article and Find Full Text PDFJ Geophys Res Space Phys
December 2024
Magnetic reconnection has been commonly reported between the solar wind IMF and the magnetic field of Earth and other planets. A similar phenomenon is expected between Jupiter's magnetosphere and Ganymede's mini magnetosphere inside the Jovian magnetosphere. This article is the first report of a reconnection event in the tail region of Ganymede.
View Article and Find Full Text PDFJ Mol Diagn
August 2024
The Tumor Mutational Burden Working Group of the Clinical Practice Committee, Association for Molecular Pathology, Rockville, Maryland; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
Tumor mutational burden (TMB) has been recognized as a predictive biomarker for immunotherapy response in several tumor types. Several laboratories offer TMB testing, but there is significant variation in how TMB is calculated, reported, and interpreted among laboratories. TMB standardization efforts are underway, but no published guidance for TMB validation and reporting is currently available.
View Article and Find Full Text PDFJCI Insight
May 2024
The Skaggs Graduate School of Chemical and Biological Science, The Scripps Research Institute, La Jolla, California, USA.
Tumor evolution is driven by genetic variation; however, it is the tumor microenvironment (TME) that provides the selective pressure contributing to evolution in cancer. Despite high histopathological heterogeneity within glioblastoma (GBM), the most aggressive brain tumor, the interactions between the genetically distinct GBM cells and the surrounding TME are not fully understood. To address this, we analyzed matched primary and recurrent GBM archival tumor tissues with imaging-based techniques aimed to simultaneously evaluate tumor tissues for the presence of hypoxic, angiogenic, and inflammatory niches, extracellular matrix (ECM) organization, TERT promoter mutational status, and several oncogenic amplifications on the same slide and location.
View Article and Find Full Text PDFSci Signal
May 2024
Department of Molecular Medicine, Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA.
Oligoadenylate synthetase 3 (OAS3) and ribonuclease L (RNase L) are components of a pathway that combats viral infection in mammals. Upon detection of viral double-stranded RNA (dsRNA), OAS3 synthesizes 2'-5'-oligo(A), which activates the RNase domain of RNase L by promoting the homodimerization and oligomerization of RNase L monomers. Activated RNase L rapidly degrades all cellular mRNAs, shutting off several cellular processes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!