Comparative genomics promises to rapidly accelerate the identification and functional classification of biologically important human genes. We developed the TIGR Orthologous Gene Alignment (TOGA;
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http://dx.doi.org/10.1101/gr.212002 | DOI Listing |
Nucleic Acids Res
January 2021
Sorbonne Université & CNRS, UMR 7144 'Adaptation & Diversity in the Marine Environment' (AD2M), Station Biologique de Roscoff (SBR), 29680 Roscoff, France.
Cyanorak v2.1 (http://www.sb-roscoff.
View Article and Find Full Text PDFPLoS One
May 2020
Institute of Tropical Agriculture and Forestry, Hainan University, Haikou, Hainan Province, China.
Trichomonas vaginalis causes the trichomoniasis, in women and urethritis and prostate cancer in men. Its genome draft published by TIGR in 2007 presents many unusual genomic and biochemical features like, exceptionally large genome size, the presence of hydrogenosome, gene duplication, lateral gene transfer mechanism and the presence of miRNA. To understand some of genomic features we have performed a comparative analysis of metabolic pathways of the T.
View Article and Find Full Text PDFBMC Mol Biol
February 2009
Dipartimento di Agrobiologia ed Agrochimica, Università della Tuscia, Via S. Camillo de Lellis, 01100 Viterbo, Italy.
Background: Usually the reference genes used in gene expression analysis have been chosen for their known or suspected housekeeping roles, however the variation observed in most of them hinders their effective use. The assessed lack of validated reference genes emphasizes the importance of a systematic study for their identification. For selecting candidate reference genes we have developed a simple in silico method based on the data publicly available in the wheat databases Unigene and TIGR.
View Article and Find Full Text PDFComp Funct Genomics
June 2010
Montclair State University, Department of Biology and Molecular Biology, 1 Normal Avenue, Montclair, NJ 07043, USA.
The ILR1-like family of hydrolase genes was initially isolated in Arabidopsis thaliana and is thought to help regulate levels of free indole-3-acetic-acid.We have investigated how this family has evolved in dicotyledon, monocotyledon and gymnosperm species by employing the GenBank and TIGR databases to retrieve orthologous genes. The relationships among these sequences were assessed employing phylogenomic analyses to examine molecular evolution and phylogeny.
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