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Letter in response to "Risk factors associated with increasing prevalence of gonorrhea and the antimicrobial susceptibility profiles of among adolescents: A decade-long, hospital-based study from India".
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Department of Dermatology, Shalby Hospital, SAS Nagar, Punjab, India.
Prolonged pediatric intensive care unit (PICU) admission, challenges in diagnosis and treatment in a child with hyper IgM syndrome in a tertiary hospital in Tanzania: a case report.
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Muhimbili National Hospital, Dar es Salaam, Tanzania.
Hyper immunoglobulin M (IgM) syndromes are a collection of uncommon primary combined immunodeficiency disorders. They are characterized by recurrent bacterial infections due to low levels of IgG, IgA, and IgE, while IgM levels remain normal or high. These conditions stem from a mutation in the CD40 ligand gene or disruptions in the CD40-signaling pathway.
View Article and Find Full Text PDFPrevalence and determinants of faecal carriage of carbapenem- and third-generation cephalosporin-resistant Enterobacterales: a cross-sectional household survey in northern Vietnam.
Lancet Reg Health West Pac
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Oxford University Clinical Research Unit (OUCRU), National Hospital for Tropical Diseases, 78 Giai Phong, Dong Da District, Hanoi, Vietnam.
Background: Antimicrobial resistance (AMR) is a silent pandemic causing 1.27 million deaths in 2019, disproportionately affecting low- and middle-income countries, but resistance among commensal microbiota and the determinants of carriage have not been widely reported. This cross-sectional household study aimed to determine the prevalence of carbapenem-resistant (CRE) and third-generation cephalosporin-resistant Enterobacterale (C3GRE) in a rural community in Ha Nam northern Vietnam, as well as the socio-demographic, behavioural, and environmental determinants of carriage.
View Article and Find Full Text PDFSilver nanoparticle-induced antimicrobial resistance in Pseudomonas aeruginosa and Salmonella spp. isolates from an urban lake.
Environ Pollut
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Department of Environmental Sciences, Southern Illinois University Edwardsville, 44 Circle Drive SW 2145, PO Box 1099, Edwardsville, IL 62026. Electronic address:
The antimicrobial properties and widespread incorporation of silver nanoparticles (AgNPs) into consumer products have raised concerns about their potential impact on public health and the environment. This study examined citrate-coated and uncoated AgNPs' antimicrobial effects on microbial growth and their potential to induce antimicrobial resistance (AMR) in the natural environment. We isolated Pseudomonas aeruginosa and Salmonella spp.
View Article and Find Full Text PDFAntimicrobial susceptibility testing of Clostridioides difficile: a dual-site study of three different media and three therapeutic antimicrobials.
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European Society of Clinical Microbiology and Infectious Diseases Study Group on Clostridioides difficile (ESGCD); Experimental Bacteriology Research Group, Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, The Netherlands. Electronic address:
Objectives: Increasing resistance to antimicrobials used for the treatment of Clostridioides difficile infections necessitates reproducible antimicrobial susceptibility testing. Current guidelines take a one-size-fits-all approach and/or offer limited guidance. We investigated how the choice of medium affects measured MIC values across two sites.
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