Living-donor lobar lung transplantation: a case study.

Crit Care Nurse

Cardiothoracic Intensive Care Unit, USC University Hospital in Los Angeles, Calif, USA.

Published: February 2000

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Objective: We report a case of pregnancy following lung transplantation (LT) for idiopathic pulmonary arterial hypertension (IPAH) in Japan.

Case Report: A female developed IPAH at 14 years of age and underwent a successful bilateral living-donor lobar LT from her parents at 19 years of age (gravida 2, para 0). At the age of 40 years, the patient became pregnant via artificial insemination.

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Objectives: This study was designed to examine the outcomes of adult living-donor lobar lung transplants (LDLLTs) using small-for-size grafts.

Methods: A calculated graft forced vital capacity of <50% of the predicted forced vital capacity of the recipient was considered to indicate a small-for-size graft. Adult recipients (≥18 years) who underwent LDLLTs between 2008 and 2022 were included in this study.

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Lobar graft evaluation in cadaveric lobar lung redo transplantation after living-donor lobar lung transplantation: a case report.

Surg Case Rep

October 2024

Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Aobaku, Sendai, Miyagi, 980-8575, Japan.

Background: Lung transplantation is a vital option for patients with end-stage lung disease. However, it faces a significant challenge due to the shortage of compatible donors, which particularly affects individuals with small chest cavities and pediatric patients. The novel approach of cadaveric lobar lung transplantation is a promising solution to alleviate the donor shortage crisis.

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Article Synopsis
  • This study investigates chronic lung allograft dysfunction (CLAD) following deceased-donor and living-donor lung transplants to unveil differences in their characteristics and prognosis.
  • Data from 123 deceased-donor and 67 living-donor lung transplants were analyzed, highlighting that living-donor transplants had fewer human leukocyte antigen mismatches and better outcomes in some clinical aspects.
  • Although living-donor transplants had a higher occurrence of restrictive allograft syndrome, overall survival rates after transplantation and post-CLAD onset were similar between both transplant groups, with living-donor grafts showing a lower cumulative incidence of CLAD compared to deceased-donor grafts.
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Background: Pulmonary Langerhans cell histiocytosis (PLCH) is a rare disorder characterized by the proliferation of Langerhans cells along the small airways, which causes nodular and cystic changes in the lung parenchyma. Lung transplantation can be a life-saving option for patients with severe respiratory failure or pulmonary hypertension. Herein, we present a case of successful lung transplantation in a patient with PLCH who developed unusually large thrombi in the central pulmonary artery.

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