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Dementia Care Practice.
Alzheimers Dement
December 2024
University of Waterloo, Waterloo, ON, Canada.
Background: Up to 30% of hospitalizations in older adults living with Mild Cognitive Impairment (MCI) and dementia are attributed to drug-related problems (DRPs), including adverse drug reactions, drug interactions, potentially inappropriate medication (PIM) use, and medication non-adherence. This study categorizes the identified DRPs according to the Pharmaceutical Care Network Europe (PCNE) Classification for DRPs version 9.1.
View Article and Find Full Text PDFThe European Drug-Drug Interaction (EuroDDI) Study Protocol: A Cross-Country Comparison of Drug-Drug Interaction Prevalence in the Older Community-Dwelling Population.
Pharmacoepidemiol Drug Saf
January 2025
School of Population Health, RCSI University of Medicine and Health Sciences, Dublin 2, Ireland.
Background: Drug-drug interactions (DDIs), highly prevalent amongst the elderly, can lead to avoidable medication-related harm. Cardiovascular and central nervous system (CNS) drugs are commonly implicated. To date, there is no consensus on how to measure DDIs, making comparisons across countries challenging.
View Article and Find Full Text PDF[Off-label psychopharmacological prescription in thirteen forensic outpatient clinics].
Tijdschr Psychiatr
January 2025
Article Synopsis
- The study examines the prevalence of off-label prescribing in outpatient forensic treatment, revealing that 72.0% of prescriptions were off-label.
- More than half (51.4%) of these off-label prescriptions were informed by existing guidelines and formularies, while 20.6% were not.
- A significant finding was that in 84.7% of the cases where off-label prescriptions did not follow guidelines, pharmacists were not consulted prior to prescribing.
How Consistent are Anti-Infective Drug Dosing Recommendations Across Three European Paediatric Formularies?
Paediatr Drugs
December 2024
PEDeus Ltd, Zurich, Switzerland.
Background: Drug dosing recommendations in paediatrics are mainly based on the age and bodyweight of the child. Because of the limited amount of label information, several paediatric drug formularies have been developed. This study compares anti-infective drug dosing recommendations across three European formularies.
View Article and Find Full Text PDFCan the Present Canadian Health Care System Provide Evidence-Based Pharmaceutical Care? Consideration of Two Important Cardiovascular Clinical Contexts.
Can J Cardiol
January 2025
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Background: Canada is the only country with universal health care lacking universal pharmaceutical care (pharmacare). Currently, a minority portion of the population has drug coverage. Furthermore, there may be discordance between provincial plans of medications that are covered.
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