Action of the calcium channels blocking agents was studied using their strong but reversible concentrations, in different regimens. Riodypine and phenihydine suppressed the contraction strength and shortened the AP duration in the myometrium muscle stripes equally effectively both in resting and under stimulation (0.3 Hz). Verapamyl and manganese ions suppressed the contraction strength and shortened the AP duration more effectively under rhythmic stimulation than in resting.
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