In rats survived systemic circulatory arrest and resuscitation, pathological changes such as increased excitability of the central nervous system and decreased volume of simultaneously acquired information considerably modulate conditioned activity. The interaction between these factors facilitates learning after formation of targeted behavioral pattern.
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http://dx.doi.org/10.1023/a:1017952105109 | DOI Listing |
Arthroplast Today
December 2024
Institute for Hygiene and Microbiology, University of Wuerzburg, Würzburg, Germany.
Background: With the rising prevalence of obesity, surgeons are frequently confronted with the problem of treating osteoarthritis of the hip via arthroplasty (total hip arthroplasty) in severely obese patients. To reduce the surgical impact, minimal-invasive approaches are often chosen. For this reason, the direct anterior approach has gained popularity but is suspected of leading to more wound complications in obese patients, especially by Gram-negative pathogens.
View Article and Find Full Text PDFDrugs R D
January 2025
Quality Evaluation Team, Samsung Bioepis Co., Ltd, Incheon, South Korea.
Background: SB17 is being developed as a biosimilar to ustekinumab reference product (RP), a human monoclonal antibody (IgG1 kappa immunoglobulin) that binds to the common p40 subunit of cytokines interleukin (IL)-23 and IL-12. Binding to this subunit prevents interaction with their receptor, resulting in modulation in the immune system responses that play a key role in inflammatory disease.
Objective: The objective of this study was to demonstrate structural, physicochemical, and biological similarity between ustekinumab RP and SB17 using various state-of-the-art analytical methods.
Mol Pharm
January 2025
Department of Pharmaceutics, School of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, United States.
With increasing prevalence globally, obesity presents unique challenges to the clinical management of other diseases. In the case of acute respiratory distress syndrome (ARDS), glucocorticoid therapy (e.g.
View Article and Find Full Text PDFImpact of climate change that stems from gaseous emissions require sustainable materials to eliminate sulfur. This study involves the modification of humic acid with magnetite nanoparticles (Fe₃O₄ NPs) by a microwave-assisted synthesis of an absorbent with reasonable pore volume and diameter for elimination of thiophenic compounds from fuel. The magnetic nano adsorbent designated Fe3O4@HA was characterized using advanced spectroscopic techniques, while their structure and morphology were analyzed through DLS, XPS, XRD, FT-IR, TGA, FESEM-EDX, VSM, and BET-N2 techniques.
View Article and Find Full Text PDFJ Alzheimers Dis
January 2025
Research Group Degenerative and Chronic Diseases, Movement, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.
The motoric cognitive risk syndrome (MCR) is a novel and clinically relevant pre-dementia syndrome indicating a higher dementia risk (e.g., for Alzheimer's disease).
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