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Association between hyponatremia and disease severity in pediatric urinary tract infections.
BMC Pediatr
November 2024
Department of Pediatrics, Chi Mei Medicine Center, No. 901, Zhonghua Road., Yongkang Dist, Tainan City, 710402, Taiwan.
Article Synopsis
- Acute urinary tract infections (UTIs) are common in children, affecting about 8% of girls and 2% of boys by age 7, with serious cases leading to acute pyelonephritis (APN).
- A study reviewed data from 344 pediatric UTI/APN patients treated from 2012 to 2022, categorizing them by serum sodium levels (hyponatremia vs. eunatremia).
- Results showed that patients with hyponatremia had higher instances of APN and abnormal kidney scans, suggesting hyponatremia might indicate a more severe UTI, although further research is needed to understand its implications.
Prevalence of bacteriuria and bacterial resistance in adolescents from the center of the state of Tlaxcala, Mexico.
Bol Med Hosp Infant Mex
November 2024
Unidad de Investigación en Nefrología y Metabolismo Mineral Óseo, Hospital Infantil de México Federico Gómez, Mexico City.
Article Synopsis
- Urinary tract infections and bacteriuria are prevalent among adolescents, with rising antibiotic resistance posing a significant health risk.
- A study in Tlaxcala, Mexico, involved 905 adolescents aged 11 to 18 and found a bacteriuria prevalence of 3.4%, primarily affecting asymptomatic individuals.
- Escherichia coli was the most common pathogen identified, with notable resistance to antibiotics, and risk factors included being female, sexually active, using contraceptives, and consuming sweetened drinks.
Asymptomatic bacteriuria screening for developing countries using a modified water quality test kit.
Appl Environ Microbiol
November 2024
Department of Microbiology and Immunology, University of South Alabama, Frederick P. Whiddon College of Medicine, Mobile, Alabama, USA.
Article Synopsis
- - Between 2% and 15% of pregnant women have asymptomatic bacteriuria (ASB), which can lead to serious pregnancy complications like pyelonephritis and low-birth weight infants, but routine screening is often missing in developing countries.
- - The Aquagenx water quality test kits, typically used for water testing, have been adapted to detect ASB in urine, showing high accuracy in clinical samples and minimal false positive and negative rates.
- - This innovative ASB screening protocol using Aquagenx not only has the potential to improve healthcare in low-resource settings but could also effectively diagnose the majority of ASB cases, as it covers 90.1% of the common causative agents.
Asymptomatic bacteriuria and its associated fetomaternal outcomes among pregnant women delivering at Bugando Medical Centre in Mwanza, Tanzania.
PLoS One
October 2024
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Article Synopsis
- * The study examined 1,093 pregnant women at Bugando Medical Center, finding that factors like anemia and prior antenatal care are linked to higher ASB risk.
- * Women with ASB showed significantly higher rates of pre-term labor, premature rupture of membranes, and low birth weight, with E. coli being the most frequent bacteria identified.
Predictive performance of urinalysis for urine culture results according to causative microorganisms: an integrated analysis with artificial intelligence.
J Clin Microbiol
October 2024
Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Urinary tract infections (UTIs) are pervasive and prevalent in both community and hospital settings. Recent trends in the changes of the causative microorganisms in these infections could affect the effectiveness of urinalysis (UA). We aimed to evaluate the predictive performance of UA for urinary culture test results according to the causative microorganisms.
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