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The Impact of Hyperbaric Oxygen Therapy on Functional and Structural Plasticity in Rats With Spinal Cord Injury.
Brain Behav
December 2024
Department of Hyperbaric Oxygen, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Introduction: Spinal cord injury (SCI) can result in sensory and locomotor function loss below the injured segment. Hyperbaric oxygen therapy (HBOT) has been proven to alleviate SCI. This study aims to establish a reproducible rat model of SCI and investigate the impact of HBOT on alterations in brain neuronal activity and neuromotor function in this experimental rat SCI model using resting-state functional magnetic resonance imaging (rs-fMRI).
View Article and Find Full Text PDFCost-effectiveness analysis of radiofrequency renal denervation for uncontrolled hypertension in Canada.
J Med Econ
December 2025
Wing Tech Inc., Menlo Park, California, USA.
Aims: Catheter-based radiofrequency renal denervation (RF RDN) is an interventional treatment for uncontrolled hypertension. This analysis explored the therapy's lifetime cost-effectiveness in a Canadian healthcare setting.
Materials And Methods: A decision-analytic Markov model was used to project health events, costs, and quality-adjusted life years over a lifetime horizon.
Article Synopsis
- * The study analyzed over 11,000 sources to assess stillbirth rates across 204 countries from 1990 to 2021, using varied definitions and gestational age benchmarks for clarity.
- * In 2021, the global stillbirth rate was 23.0 per 1,000 births at 20 weeks or longer, with a neonatal mortality rate of 17.1 per 1,000 live births, indicating a concerning level of both stillbirths and neonatal deaths worldwide.
Cost-Effectiveness of Radiofrequency Renal Denervation for Uncontrolled Hypertension in Japan.
J Clin Hypertens (Greenwich)
December 2024
Wing Tech Inc., Menlo Park, California, USA.
Radiofrequency renal denervation (RF RDN) is a novel therapy for uncontrolled hypertension. In the recent sham-controlled SPYRAL HTN-ON MED study, office-based systolic blood pressure (oSBP) and nighttime BP were reduced significantly. This study examined the cost-effectiveness of RF RDN in the context of the Japanese healthcare system based on this latest clinical evidence.
View Article and Find Full Text PDFThe Best DFT Functional Is the Ensemble of Functionals.
Adv Sci (Weinh)
December 2024
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, Xiamen University, Xiamen, Fujian, 361005, China.
The development of better density functional theory (DFT) methods is one of the most active research areas, given the importance of DFT for ubiquitous molecular and materials simulations. However, this research primarily focuses on improving a specific exchange-correlation Kohn-Sham density functional. Here, a robust procedure is proposed for constructing transferable ensembles of density functionals that perform superior to any constituent individual density functional.
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