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Alzheimer's disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA roles.
Front Neurosci
January 2025
Critical Care Quality Improvement Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alzheimer's Disease (AD) is the most prevalent type of dementia and is characterized by the presence of senile plaques and neurofibrillary tangles. There are various theories concerning the causes of AD, but the connection between viral and bacterial infections and their potential role in the pathogenesis of AD has become a fascinating area of research for the field. Various viruses such as (HSV-1), (EBV), Cytomegalovirus (CMV), influenza viruses, and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), as well as bacteria such as (CP), (HP), (), Spirochetes and eukaryotic unicellular parasites (e.
View Article and Find Full Text PDFComparison Between Indirect Fluorescent Antibody Test and Modified Agglutination Test for Detecting Anti-Toxoplasma gondii IgG Antibodies in Neotropical Primates.
J Med Primatol
February 2025
School of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Background: Toxoplasma gondii is a zoonotic parasite with a great impact on the health of Neotropical primates (NP). The aim of this study was to compare the agreement between the immunofluorescent antibody test (IFAT) and the modified agglutination test (MAT) to detect IgG anti-T. gondii antibodies in NP.
View Article and Find Full Text PDFSynanthropic Rodents as Bioindicator of Human Pathogens in a Tourist Area of Brazil.
Ecohealth
January 2025
Department of Agricultural and Environmental Sciences, State University of Santa Cruz, Direction of the University: Campus Soane Nazaré de Andrade, Rod. Jorge Amado, Km 16 - Salobrinho, Ilhéus, Bahia, 45662-900, Brazil.
The black rat Rattus rattus is an exotic and synanthropic rodent prominent in Brazil and with high adaptation to urban areas. The species have an omnivorous diet feed on human food resources, potentially becoming infected and spreading infectious agents that cause zoonoses such as leptospirosis, leishmaniosis, Chagas disease, and toxoplasmosis, which are significant public health concerns in the country. We analyzed the epidemiologic profile of R.
View Article and Find Full Text PDFSeroprevalence of anti-ToxoplasmaIgG among the human population in Indonesia: a systematic review and meta-analysis.
BMC Public Health
January 2025
Medicine Program, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Background: Toxoplasma gondii is a ubiquitous parasite that can cause significant complications when it infects pregnant women and immunocompromised patients. These complications include miscarriage, fetal abnormalities, and fatal cerebral toxoplasmosis. Despite its significance, the true burden of toxoplasmosis in Indonesia remains underexplored.
View Article and Find Full Text PDFToxoplasmosis is a significant food-borne protozoal disease in humans and animals. The study aimed to find out Toxoplasma seropositivity in sheep, estimate epidemiological risk factors and assess haemato-biochemical parameter changes. Blood samples were collected from 276 indigenous sheep in five districts surrounding Sulaymaniyah Province in the northern region of Iraq.
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