The phenomenon of cross-resistance to antiretroviral agents used to treat human immunodeficiency virus type 1 infection is well known but so far has been only qualitatively described. Here, we quantitate the degree of cross-resistance among all commonly prescribed antiretroviral agents in almost 5,000 clinically derived recombinant isolates collected in the United States since January 2000.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127474PMC
http://dx.doi.org/10.1128/AAC.46.3.909-912.2002DOI Listing

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