Four new naphthohydroquinones, rubinaphthins A (1), B (2), C (3), and D (4), together with 11 known compounds were isolated and characterized from the roots of Rubia yunnanensis. The structures of 1-4 were elucidated by spectral analysis and chemical transformation.
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Identification of New Compounds from the Roots of Rubia tibetica Hook. f.
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Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, 211189, PR China.
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View Article and Find Full Text PDF[Syntheses and Structure-Activity Relationship Studies of Antitumor Bicyclic Hexapeptide RA-VII Analogues].
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Fitoterapia
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Two unprecedented quinone compounds Rubiaxylm A (1) and Rubiaxylm B (2), along with fifteen known anthraquinones (3-17) were isolated and characterized from the roots of Rubia tibetica in Tibetan medicine. Their structures were identified through comprehensive analyses of 1D/2D NMR as well as HR-ESIMS data. Furthermore, all separated compounds were evaluated for their cytotoxic activity on A549, Caco-2, MDA-MB-231 and Skov-3 cell lines.
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