We report the synthesis and radioligand binding analysis of a series of naphthalenic melatonin receptor ligands, N-[2-(7-alkoxy-2-methoxy-1-naphthyl)ethyl]propionamide. This series of ligands exhibits subpicomolar binding affinity to both MT1 and MT2 melatonin receptors expressed in chinese hamster ovary (CHO) cells.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.50.272 | DOI Listing |
Publication Analysis
Top Keywords
melatonin receptor
8
receptor ligands
8
synthesis pharmacological
4
pharmacological analysis
4
analysis high
4
high affinity
4
affinity melatonin
4
ligands report
4
report synthesis
4
synthesis radioligand
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!