[Perihepatitis and HIV/AIDS infection. Apropos of 13 cases at the National Hospital of Bobo-Dioulasso].

Bull Soc Pathol Exot

Service d'hépato-gastro-entérologie, Hôpital national de Ouagadougou, BP 7022, Burkina-Faso.

Published: November 2001

AI Article Synopsis

  • Perihepatitis, also known as Fitz-Hugh syndrome, is a rare condition often linked to HIV-AIDS, and this study focuses on its incidence in patients experiencing right hypochondrial pain.
  • A retrospective study conducted in Burkina-Faso analyzed 130 laparoscopies between 1997-1999, revealing 13 diagnosed cases of perihepatitis, predominantly in women (11 out of 13).
  • All identified patients were HIV positive, with clinical symptoms showing a strong connection between immunodepression and the occurrence of perihepatitis, highlighting its significance as an opportunistic illness in this population.

Article Abstract

Perihepatitis or Fitz-Hugh syndrome, peritonitis located in the right hypochondriasis (RH), is a relatively rare affectation. However, the HIV-AIDS pandemic has brought about the emergence and re-emergence of disease-states either uncommon or formerly on the decline as well as the appearance of opportunistic illness. We report the results of a retrospective study conducted in the National Hospital of Bobo-Dioulasso (Burkina-Faso) between 1 June 1997 and 31 December 1999 in an effort to contribute to a wider vision of diseases associated with HIV-AIDS. We based our study on 130 laparoscopies carried out for unexplained pain linked to RH (with or without fever), as well as abdominal-pelvian or diffuse abdominal pain. Thirteen cases (11 women, 2 men) of perihepatitis were diagnosed. The mean age for women and men was respectively 31.4 and 39.5. HIV serology was systematically carried out for all patients and, in case of perihepatitis, cultures were taken. All patients were infected with HIV and some presented signs of AIDS according to the WHO classification. In clinical terms, a shalking pain for RH was noted for 5 patients, abdominal sensitivity in 8 cases as well as gynaecological anomalies: cul-de-sac moving pain (4 cases), leuchorrea (3 cases) and mucosic vulvovaginitis (1 case). Paraclinical tests revealed a slight hepatic cytolysis for only 3 patients (1.5 N). 6 patients tested positive for Chlamydia trachomatis; the 7 others could not be tested, but this aetiology was assumed for evaluating the efficacy of the treatment under study. The high frequency of perihepatitis in these patients, all of whom were suffering from HIV-AIDS, and its presence in the 2 male cases, suggest that immunodepression is conducive to the appearance of this disease.

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