AI Article Synopsis
- - The study involved 49 patients in a neonatal intensive care unit and found that catheters flushed with heparinized saline had a significantly longer time to failure (median = 127 hours) compared to those flushed with normal saline (median = 39 hours) with a p-value of 0.0358.
- - There was no significant difference in the mean scores for catheters flushed with heparin (M = 41.5 hours) versus those flushed with saline (M = 30.4 hours) among catheters removed for non-treatment reasons, with a p-value of 0.841.
- - The study suggests that survival time analysis is crucial for assessing time-dependent research outcomes where the endpoint
Article Abstract
In this randomized double-blind experiment of 49 neonatal intensive care unit patients, probable time to catheter failure was significantly longer (p =.0358) for catheters flushed with heparinized saline (median = 127) compared with those flushed with normal saline (median = 39). This is in contrast to the nonsignificant difference (p =.841) in mean scores for six heparin-flushed catheters (M = 41.5 hours, SD = 44.0) compared with 18 saline-flushed catheters (M = 30.4 hours, SD = 20.8) discontinued for reasons other than completion of treatment. We concluded that survival time analysis is necessary when evaluating results of time-dependent studies in which the end point may not be elective.
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| http://dx.doi.org/10.1053/apnr.2002.29520 | DOI Listing |
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