The potential of bioaffinity as a tool for the study of biological-recognition mechanisms is gaining increasing value. The search continues for alternative products that can be obtained from renewable sources, such as the bark exudate gum from the cashew tree (Anacardium occidentale L.), which grows wild in many tropical and subtropical countries. Its potential use as a chromatographic matrix and/or for bioaffinity ligand for proteins (lectins) has been investigated. The crude gum was cross-linked in order to obtain a kind of chromatographic matrix (gel). To evaluate the gum's ability to retain glycoproteins (lectins), affinity chromatography was performed and, in addition, the reological behaviour of the gum was characterized.
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http://dx.doi.org/10.1042/ba20010024 | DOI Listing |
Mol Omics
January 2025
Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.
Lung cancer remains the leading cause of cancer-related deaths worldwide due to its poor prognosis. Despite significant advancements in the understanding of cancer development, improvements in diagnostic methods, and multimodal therapeutic regimens, the prognosis of lung cancer has still not improved. Therefore, it is reasonable to look for newer and alternative medicines for treatment.
View Article and Find Full Text PDFNutr Hosp
December 2024
Nursing. Oswaldo Cruz Foundation.
Background: cashew nut is an almond known for its cardiovascular benefits in adults and weight gain effects in malnourished children, as supported by research. However, its impact on overweight children remains unexplored.
Objective: to analyze the effect of consuming biscuits made with cashew nut flour on the blood glucose and serum triglyceride levels of children with overweight/obesity over four weeks.
Phytother Res
December 2024
Chitkara University School of Pharmacy, Chitkara University, Himachal Pradesh, India.
Diabetes mellitus is a chronic metabolic disorder marked by hyperglycemia, resistance to insulin, and impaired function of the pancreatic β-cells; it advances into more serious complications like nephropathy, neuropathy, cardiovascular disease, and retinopathy; herbal medicine has indicated promise in not just mitigating the symptoms but also in managing the complications. This review would aim to evaluate the pharmacological aspect of the botanical therapies Anacardium occidentale, Allium sativum, Urtica dioica, and Cinnamomum zeylanicum, as well as their bioactive phytochemicals, quercetin, resveratrol, berberine, and epigallocatechin gallate (EGCG). In this review, we discuss their mechanisms for secreting the insulin sensitizers, carbohydrate-hydrolyzing enzymes, reduction in oxidative stress and effectiveness against diabetic complications-all through sensitivity to insulin.
View Article and Find Full Text PDFAnimals (Basel)
November 2024
Key Laboratory of Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
To evaluate the phytobiotic effect of leaf powder (AOLP) on growth performance, diarrhea incidence, blood biochemistry, and intestinal traits, seventy-two weaned piglets were randomly distributed into four groups (six replicates/group and three pigs/replicate) for 28 days, receiving a control diet (T0) or being supplemented with 5 (T1), 10 (T2), or 15 (T3) g/kg of AOLP. The diets did not affect the growth performance ( > 0.05); however, the AOLP groups had a decreased diarrhea incidence and malondialdehyde concentration ( < 0.
View Article and Find Full Text PDFBiol Pharm Bull
December 2024
Faculty of Pharmaceutical Sciences, Tokushima Bunri University.
Anacardic acid (AA) was first detected in the shells of cashew nuts, Anacardium occidentale, and is known to possess inhibitory activity against acetyltransferases. Recently, several anacardic acid derivatives (AAds) were isolated from the wild fungus, Tyromyces fissilis, which has been reported as xanthine oxidase inhibitors. In the present study, we investigated whether nine AAds function as acetyltransferase inhibitors.
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