Type 2 diabetes is a common, chronic disease, with a high risk of macrovascular and microvascular complications that lead to premature death and disability. The disease is managed largely in primary care and its rising prevalence will increase the workload of community nurses. The forthcoming Diabetes National Service Framework will aim to improve the standards of diabetic care, while scientific and technological developments offer new treatments that may also improve the outlook for patients. There is as yet no case for population screening for type 2 diabetes, but community nurses are ideally placed to carry out local screening initiatives based on consensus guidelines.
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http://dx.doi.org/10.12968/bjcn.2001.6.11.9458 | DOI Listing |
JAMA Netw Open
January 2025
Healthcare Transformation Institute, Department of Medical Ethics and Health Policy, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Importance: Adherence to glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is important for their effectiveness. Discontinuation and reinitiation patterns are not well understood.
Objective: To describe rates of and factors associated with discontinuation and subsequent reinitiation of GLP-1 RAs among adults with overweight or obesity.
J Endocrinol Invest
January 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (MI), Via Rita Levi Montalcini 4, Milan, Italy.
Purpose: The real-world effectiveness of switching from denosumab to romosozumab remains controversial. Sequential therapy with romosozumab was shown to be associated with inadequate suppression of bone resorption and there was anecdotal evidence of major osteoporotic fractures (MOFs) after transitioning from denosumab to romosozumab. This study evaluated the effects on bone resorption of early romosozumab administration 3 months after denosumab withdrawal in fractured women with post-menopausal osteoporosis.
View Article and Find Full Text PDFDiabetologia
January 2025
Department of Diabetes and Endocrinology, Medical University of Graz, Graz, Austria.
Aim/hypothesis: Pilots with type 1 diabetes are required to perform capillary glucose monitoring regularly during flights. Continuous glucose monitoring (CGM) may be an effective and more practical alternative. This study aimed to assess the accuracy of CGM systems against self-monitoring of blood glucose (SMBG) during a hypobaric flight simulation.
View Article and Find Full Text PDFCatheter Cardiovasc Interv
January 2025
Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia, USA.
Patients with type 2 diabetes mellitus (DM) are more susceptible to microvascular complications. However, whether DM is associated with coronary microvascular dysfunction (CMD) is unclear. This observational study used data from the Coronary Microvascular Disease Registry (CMDR) (NCT05960474) and included patients with angina and no obstructive coronary artery disease (ANOCA) who underwent invasive CMD evaluation using the CoroVentis CoroFlow System (Abbott Vascular, Santa Clara, CA).
View Article and Find Full Text PDFDiabetes Obes Metab
January 2025
Section of Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
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