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Several Chlamydia trachomatis lineages identified through outer membrane protein A genotyping or multilocus sequence typing have been circulating worldwide among men who have sex with men. In a study in Tokyo, Japan, we demonstrate that such lineages commonly belong to a specific polymorphic membrane protein E clade across genotypes.
View Article and Find Full Text PDFPlethora of New Marsupial Genomes Informs Our Knowledge of Marsupial MHC Class II.
Genome Biol Evol
August 2024
School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales 2006, Australia.
The major histocompatibility complex (MHC) plays a vital role in the vertebrate immune system due to its role in infection, disease and autoimmunity, or recognition of "self". The marsupial MHC class II genes show divergence from eutherian MHC class II genes and are a unique taxon of therian mammals that give birth to altricial and immunologically naive young providing an opportune study system for investigating evolution of the immune system. Additionally, the MHC in marsupials has been implicated in disease associations, including susceptibility to Chlamydia pecorum infection in koalas.
View Article and Find Full Text PDFUnpredictable soil conditions can affect the prevalence of a microbial symbiosis.
PeerJ
May 2024
Department of Biology, Washington University in St. Louis, St. Louis, MO, United States.
The evolution of symbiotic interactions may be affected by unpredictable conditions. However, a link between prevalence of these conditions and symbiosis has not been widely demonstrated. We test for these associations using social amoebae and their bacterial endosymbionts.
View Article and Find Full Text PDFArticle Synopsis
- A national study in Spain examined the mpox outbreak, focusing on the clinical profiles and management strategies in place.
- Around 1,472 patients were analyzed, predominantly cisgender men, with sexual transmission as the main route and a significant population having HIV-related immunosuppression.
- Most patients displayed common symptoms like rash and fever, with one-third receiving no treatment, while others were treated with various therapies, indicating a need for better preventive measures and healthcare responses.
Diversity and genetic characterization of Chlamydia isolated from Siamese crocodiles (Crocodylus siamensis).
Acta Trop
May 2024
Monitoring and Surveillance Center for Zoonotic Diseases in Wildlife and Exotic Animals, Faculty of Veterinary Science, Mahidol University, Nakhon Pathom, Thailand. Electronic address:
Chlamydiosis, an infection caused by several Chlamydia species, has been reported in Nile, saltwater, and Siamese crocodiles. Despite its widespread reports in various countries, including Thailand, genetic information on Chlamydia species remains limited. This study presents a whole-genome-based characterization of Siamese crocodile-isolated Chlamydia.
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