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| http://dx.doi.org/10.1136/ard.61.3.281 | DOI Listing |
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Relationship between antihistamine residues in wastewater and airborne pollen concentrations: Insights into population-scale pollinosis response.
Sci Total Environ
January 2025
Swiss Federal Institute of Aquatic Science and Technology, Eawag, Dübendorf, Switzerland.
Pollinosis is the most prevalent allergic disorder. Assessing the impact of real-world pollen exposure on symptoms remains challenging due to extensive patient-level efforts required. This study explores the potential of wastewater-based epidemiology (WBE) to investigate the relationship between airborne pollen concentrations and antihistamine residues in wastewater as an indicator of pollinosis symptom treatment at the population-scale.
View Article and Find Full Text PDFGradient disparities in allergy and the gut microbiome among rural, migrant, and urban populations across China.
World Allergy Organ J
January 2025
Department of Respiratory Medicine, Guangzhou Institute of Respiratory Health, China State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, China.
Background: While much of the evidence linking the rapid urbanization and the increasing prevalence of allergen sensitization, but little is known regarding rural-to-urban migrants. The aim of this study was to identify the disparities in allergy, the gut microbiome and factors among native urban, migrating, and native rural Chinese.
Methods: We redesigned the dataset of the China Alliance of Research on Respiratory Allergic Disease secondary survey, and after stratified sampling, a subsample of 2422 subjects were enrolled for the analysis of a questionnaire, skin prick tests (SPT), and specific immunoglobulin E (sIgE) titer measurements against 8 common allergens.
Biologic therapies targeting type 2 cytokines are effective at improving asthma symptoms and control-a systematic review and meta-analysis.
J Allergy Clin Immunol Glob
February 2025
School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Background: Allergic asthma is a highly prevalent chronic inflammatory disease driven by aeroallergen exposure. In severe asthma, the current standard of care does not fully control disease symptoms, indicating an unmet clinical need. Biologic therapies targeting cytokines IL-4, IL-5, and IL-13 have been shown to provide benefits to asthmatic patients over currently existing asthma treatments.
View Article and Find Full Text PDFImpact of Birth Order on Paediatric Allergic Diseases: A National Birth Cohort in Japan.
Clin Exp Allergy
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Department of Pediatrics, Okayama University, Graduate School of Medicine, Density and Pharmaceutical Science, Okayama, Japan.
Sex hormones and allergies: exploring the gender differences in immune responses.
Front Allergy
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Research Institute of Biomedical Sciences, University Center of Health Sciences, University of Guadalajara, Guadalajara, Mexico.
Allergies are closely associated with sex-related hormonal variations that influence immune function, leading to distinct symptom profiles. Similar sex-based differences are observed in other immune disorders, such as autoimmune diseases. In allergies, women exhibit a higher prevalence of atopic conditions, such as allergic asthma and eczema, in comparison to men.
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