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Renal failure due to rectal neoplastic polyp: McKittrick-Wheelock syndrome-a case report.
J Med Case Rep
January 2025
Department of Surgery, University Hospital "Tsaritsa Joanna - ISUL", Medical University, Str. "Byalo More" No 8, Sofia, Bulgaria.
Background: McKittrick-Wheelock syndrome is an uncommon and severe disorder caused by large hypersecretory tumors located in the distal colorectal area. Excessive secretion from adenomas is an unusual clinical manifestation that leads to severe electrolyte and fluid depletion, subsequently resulting in kidney injury. Successful treatment relies on quick and cooperative decision-making for timely intervention.
View Article and Find Full Text PDFProximal Polyps Are Associated With Higher Incidence of Colorectal Cancer: Analysis of the Minnesota Colon Cancer Control Study.
Am J Gastroenterol
December 2024
Division of Environmental Health Sciences, University of Minnesota, Minneapolis, Minnesota, USA.
Introduction: Despite reports indicating that polyps proximal to the splenic flexure have higher rates of metachronous colorectal adenocarcinoma (CRC), the role of adenoma location on surveillance recommendations remains unclear. This study aimed to analyze the association between index polyp location and postcolonoscopy CRC among participants of the Minnesota Colon Cancer Control Study.
Methods: The Minnesota Colon Cancer Control Study randomized 46,551 patients 50-80 years to usual care, annual, or biennial screening with fecal occult-blood testing.
Duodenal Traditional Serrated Adenoma: A Case Report and Literature Review.
Cureus
October 2024
Gastroenterology, Faculdade de Medicina, Universidade de Sao Paulo, Serviço de Endoscopia Gastrointestinal do Hospital das Clínicas, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, BRA.
Traditional serrated adenomas (TSAs) of the duodenum are rare lesions with potential for malignant transformation. We present the case of a 44-year-old female with a history of bariatric surgery who presented with worsening abdominal pain, nausea, and significant weight loss. Imaging studies, including MRI, revealed a 3.
View Article and Find Full Text PDFSignificant Missed Polyps in the UK Bowel Cancer Screening Programme (BCSP): A Retrospective Analysis of Prevalence and Contributing Factors.
Cureus
October 2024
Gastroenterology, Macclesfield District General Hospital, Macclesfield, GBR.
Background Colorectal cancer (CRC) remains a significant public health challenge. Patients having abnormal faecal immunochemical test (FIT) results are offered a colonoscopy. The effectiveness of colonoscopies can, however, often be challenged by the occurrence of missed polyps.
View Article and Find Full Text PDFInterval Advanced Adenomas and Neoplasia in Patients with Negative Colonoscopy Following Positive Stool-Based Colorectal Cancer Screening Test.
Dig Dis Sci
November 2024
Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, MS: BCM 285, Houston, TX, USA.
Background/aims: Fecal occult blood test (FOBT) and fecal immunohistochemical test (FIT) are used for colorectal cancer (CRC) screening. However, when no adenomas are found following a positive FOBT/FIT, the future risk of advanced adenomas or colorectal cancer (CRC) is unclear. We determined the incidence and determinants of advanced adenomas or CRC after a negative index colonoscopy following a positive FOBT/FIT.
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