MAP kinase cascades: scaffolding signal specificity.

Curr Biol

Swiss Institute for Experimental Cancer Research (ISREC), Ch. des Boveresses 155, 1066, Epalinges/VD, Switzerland.

Published: January 2002

Scaffold proteins organize many MAP kinase pathways by interacting with several components of these cascades. Recent studies suggest that scaffold proteins provide local activation platforms that contribute to signal specificity by insulating different MAP kinase pathways.

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http://dx.doi.org/10.1016/s0960-9822(01)00672-8DOI Listing

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