Male breast cancer represents a sporadic oncological disease (0.2-1.5%), with a very rare incidence (200 times lower) compared to omologous condition in women. Low incidence, early metastasizing chances, due to particular anatomic structure of the male gland, offering a high invasiveness rate to surrounding tissues are responsible of a late diagnosis, for which an histopathological response in case of malignant suspect, should be mandatory as well as poor prognostic expectations, in case of lymphnodes positivity (5 year-survival, after radical mastectomy: 17-60%), which unfortunately accounts for 50% of the patients at diagnosis. The difference with the success obtained in the treatment of female breast cancer, is striking, caused by the absence of a standard therapy and, on the other hand, of any screening programs.
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