Twenty patients suffering from chronic obstructive bronchopulmonary disease were tested during exercise. If exhaustive load is always reduced; it is difficult to predict from the functional results obtained at rest. The commun characteristic found in those patients is the insufficient adaptation during exercise of the VA/V ratio, with deterioration of Pao2 and Paco2. Acidosis is constant and mixed both metabolic and respiratory. The results are discussed after review of the literature.
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