Objective: The Hammersmith Infant Neurological Examination was performed in a cohort of 74 preterm infants whose gestational age ranged between 24 and 30.5 weeks. The infants were examined between 9 and 18 months' chronologic age (6-15 months' corrected age) and scored with the optimality score system previously standardized in a cohort of low-risk term infants. The aim of the study was to establish the frequency distribution of the optimality scores in this cohort and to establish whether the scores can predict locomotor function at 2 years of age.
Results: The results showed that this standardized neurologic examination can be performed in preterm infants as early as 9 months' chronologic age to predict motor outcome at 2 years old. The scores showed no significant association with the degree of prematurity or the age of assessment.
Conclusion: This examination should be particularly useful in very premature infants who are at high risk of severe neurologic and developmental disabilities and for whom the early prediction of motor function can be difficult.
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http://dx.doi.org/10.1067/mpd.2002.119626 | DOI Listing |
J Perinatol
January 2025
Neonatal Intensive Care Unit, Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen, 518028, Guangdong Province, China.
Objective: The aim of this study was to examine the predictive value of the lung ultrasound score (LUS) for successful extubation in preterm infants born at ≤25 weeks.
Methods: This was a single-center, prospective cohort study. Preterm infants with gestational age (GA) ≤ 25 weeks who received invasive mechanical ventilation (IMV) for ≥72 h were included.
Pediatr Obes
January 2025
Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Background: Studies on how birth body mass index (BMI) affects health outcomes in preterm infants are relatively limited.
Aim: To analyze the association between BMI at birth and neonatal health outcomes in extremely low and very low birth weight preterm infants in China.
Methods: Used data from the Chinese Premature Infant Informatization Platform (2022-2023).
BMJ Case Rep
January 2025
Department of Paediatric Surgery, KK Women's and Children's Hospital, Singapore.
We report a case of small bowel perforation from ileo-ileal intussusception with necrotising enterocolitis (NEC) after indomethacin exposure mimicking spontaneous intestinal perforation in an extremely preterm neonate. Indomethacin exposure can cause mesenteric hypoperfusion, resulting in an ischaemic lead point for intussusception and NEC. We advocate that intussusception should be considered as one of the differentials for neonates with recurrent feeding intolerance postindomethacin exposure.
View Article and Find Full Text PDFEarly Hum Dev
January 2025
Department of Neonatology, Máxima Medical Center, Veldhoven, Noord-Brabant, the Netherlands.
Background: Although preterm birth is associated with deficits in both motor and cognitive functioning, the association between early motor skills and cognitive outcomes at a later age remains underexplored.
Aim: To evaluate associations between motor skills at age 5.5 and cognitive functioning at age 8.
PLoS One
January 2025
Department of Medical Sciences, Cancer Epidemiology Unit, University of Turin and CPO-Piemonte, Turin, Italy.
Objectives: Maternal occupational exposures during early pregnancy can be detrimental to foetus health and have short- and long-term health effects on the child. This study examined their association with adverse birth outcomes.
Methods: The study included 3938 nulliparous women from the Italian NINFEA mother-child cohort.
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