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Impact of disease duration and surgical intervention on arousal networks in temporal lobe epilepsy.
J Neurosurg
January 2025
Departments of1Biomedical Engineering.
Objective: Epilepsy is a common neurological disease affecting nearly 1% of the global population, and temporal lobe epilepsy (TLE) is the most common type. Patients experience recurrent seizures and chronic cognitive deficits that can impact their quality of life, ability to work, and independence. These cognitive deficits often extend beyond the temporal lobe and are not well understood.
View Article and Find Full Text PDFPosterior extent of left anterior temporal lobectomy and picture naming decline.
J Neurosurg
January 2025
1Service de Neurochirurgie, Université de Lorraine, CHRU-Nancy.
Objective: Recent voxel-based lesion symptom mapping (VLSM) studies have identified a critical region for picture naming, located 3.4 to 6.1 cm from the temporal pole.
View Article and Find Full Text PDFThe impact of resective epilepsy surgery on the brain network: evidence from post-surgical imaging.
Brain
January 2025
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37240, USA.
Resective epilepsy surgery can be an effective treatment for patients with medication-resistant focal epilepsy. Epilepsy resection consists of the surgical removal of an epileptic focus to stop seizure generation and disrupt the epileptic network. However, even focal surgical resections for epilepsy lead to widespread brain network changes.
View Article and Find Full Text PDFRedefining diagnostic lesional status in temporal lobe epilepsy with artificial intelligence.
Brain
January 2025
Department of Neurology, University of South Carolina, Columbia, SC 29203, USA.
Despite decades of advancements in diagnostic MRI, 30-50% of temporal lobe epilepsy (TLE) patients remain categorized as "non-lesional" (i.e., MRI negative or MRI-) based on visual assessment by human experts.
View Article and Find Full Text PDFMachine Learning-Based Diagnosis of Chronic Subjective Tinnitus With Altered Cognitive Function: An Event-Related Potential Study.
Ear Hear
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Ansan Hospital, Korea University College of Medicine, Republic of Korea.
Objectives: Due to the absence of objective diagnostic criteria, tinnitus diagnosis primarily relies on subjective assessments. However, its neuropathological features can be objectively quantified using electroencephalography (EEG). Despite the existing research, the pathophysiology of tinnitus remains unclear.
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