Study Design: A prospective test-retest study was conducted to investigate both new and follow-up patients with low back pain presenting to an orthopedic surgeon specializing in back pain.
Objectives: To further validate the internal consistency and test-retest reliability of the Low Back Outcome Score, and to compare these results with other condition-specific disability scales.
Summary Of Background Data: To be useful in clinical practice, health-specific questionnaires must demonstrate reliability and validity. Several disease-specific questionnaires for low back pain have been validated to different extents.
Methods: In this study, 102 new and 42 follow-up patients consecutively attending a consultant clinic completed the Low Back Outcome Score on their visit, then again after an interval of 1 week in postal form. This instrument also was completed by 230 patients presenting to a physiotherapist.
Results: A response rate of 90% was achieved for the postal questionnaire. A test of internal consistency conducted with the study sample achieved a Cronbach alpha coefficient of 0.85. Overall agreement for test-retest reliability was 84%, and the reliability coefficient (K) reached a range of 0.51 to 0.86 (P < 0.05). A Bland/Altman plot was calculated, demonstrating that only 5% of patient scores change by more than 11.6 scale points between test and retest, which is not sufficient to change outcome categories.
Conclusion: The Low Back Outcome Score appears to have good internal consistency and test-retest reliability for use in clinical practice.
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http://dx.doi.org/10.1097/00007632-200201150-00017 | DOI Listing |
JMIR Form Res
January 2025
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Background: The potential of telehealth psychotherapy (ie, the online delivery of treatment via a video web-based platform) is gaining increased attention. However, there is skepticism about its acceptance, safety, and efficacy for patients with high emotional and behavioral dysregulation.
Objective: This study aims to provide initial effect size estimates of symptom change from pre- to post treatment, and the acceptance and safety of telehealth dialectical behavior therapy (DBT) for individuals diagnosed with borderline personality disorder (BPD).
Neurology
February 2025
Department of Neurology, Yale University School of Medicine, New Haven, CT.
Background And Objectives: The most effective antiseizure medications (ASMs) for poststroke seizures (PSSs) remain unclear. We aimed to determine outcomes associated with ASMs in people with PSS.
Methods: We systematically searched electronic databases for studies on patients with PSS on ASMs.
JCO Clin Cancer Inform
January 2025
SimBioSys Inc, Chicago, IL.
Purpose: Perfusion modeling presents significant opportunities for imaging biomarker development in breast cancer but has historically been held back by the need for data beyond the clinical standard of care (SoC) and uncertainty in the interpretability of results. We aimed to design a perfusion model applicable to breast cancer SoC dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) series with results stable to low temporal resolution imaging, comparable with published results using full-resolution DCE-MRI, and correlative with orthogonal imaging modalities indicative of biophysical markers.
Methods: Subsampled high-temporal-resolution DCE-MRI series were run through our perfusion model and resulting fits were compared for consistency.
J Clin Gastroenterol
January 2025
Department of Gastroenterology and Hepatology Creighton University, Omaha, NE.
Introduction: Thermal ablative methods (such as argon plasma coagulation (APC) and soft tip snare coagulation (STSC) are commonly used to treat polyp margins. We aim to appraise the current literature and compare clinical outcomes between patients with treated (with APC vs. STSC) and non-treated endoscopic mucosal resection (EMR) margins.
View Article and Find Full Text PDFChemphyschem
January 2025
Durgapur Government College, Department of Chemistry, INDIA.
The relative reactivity and cis/trans selectivity of the intramolecular [3+2] cycloaddition (IM32CA) reactions of nitrile oxide (NO), azide (AZ), nitrile sulfide (NS) and nitrile ylide (NY), leading to functionalized heterocycles are studied within the Molecular Electron Density Theory. The kinetically controlled IM32CA reactions are predicted to be cis stereospecific, while the reaction feasibility follows the order NY > NS > NO > AZ with the respective activation Gibbs free energies of 13.7, 17.
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