Using the method of column chromatography the content of adenyl nucleoptides in the muscle and liver homogentates was determined in the rats subjected to short-lasting, intensive physical exercise. Following the exercise a slight increase in AMP and a decrease in ATP levels were found in the liver. In the muscles the levels of AMP and ADP increased while the level of ATP decreased markedly.
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Background: Cannabis is increasingly used and debates about the legalisation of the recreational use of cannabis are ongoing. In this prospective, placebo-controlled study in healthy volunteers not regularly consuming cannabis, subjective psychotropic and somatic effects after a single dose of intravenous THC were assessed and quantified over 48 h.
Methods: Twenty-five healthy volunteers received a single IV bolus of THC and 6 received normal saline.
Medicina (B Aires)
December 2024
Clínica La Pequeña Familia, Junín, Buenos Aires, Argentina.
Western equine encephalitis is a zoonotic viral disease transmitted by the bite of an infected mosquito. Humans are terminal hosts and since they develop a very low and short lasting viremia, they are incapable of transmitting the disease. Most cases are asymptomatic, but it can present with high fever, myalgia and encephalitis or meningitis.
View Article and Find Full Text PDFFolia Neuropathol
February 2024
Department of Neurology and Epileptology, The Children's Memorial Health Institute, Warsaw, Poland.
Introduction: Drug-resistant epilepsy in infancy and childhood is a devastating condition, frequently associated with neuropsychiatric comorbidities. West syndrome is one of the most severe epilepsy syndromes. Adrenocorticotropic hormone (ACTH) treatment is recommended in such cases, but its mechanism of action is still unknown.
View Article and Find Full Text PDFNeurophysiol Clin
February 2023
Service de néonatalogie CHU Lille, Lille, France.
Objectives: Controlled therapeutic hypothermia (CTH) is a standard of care in the management of neonatal hypoxic-ischemic encephalopathy HIE in newborns after 36 weeks of gestational age (WGA) in France. The electroencephalogram (EEG) plays a major role in HIE diagnosis and follow-up. We conducted a French national survey on the current use of EEG in newborn undergoing CTH.
View Article and Find Full Text PDFMinerva Anestesiol
June 2023
Department of Anesthesia and Intensive Care Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Background: Flow-controlled ventilation (FCV) represents a novel ventilation method, which guarantees a continuous gas flow during inspiration and expiration. Long term comparison to volume- and pressure-controlled ventilation (PCV) after five- and ten hours have shown improved gas exchange parameters and lung tissue aeration. Aim of this porcine trial was to compare gas exchange parameters and lung tissue aeration in short time application of FCV compared to PCV to determine effects which will most probably pertain in short lasting procedures under general anesthesia.
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