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1950s-1990s: The pioneering era of insect neuroscience in Uruguay.
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Departamento de Neurofisiología Celular y Molecular, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay. Electronic address:
Insect research has significantly advanced neuroscience by addressing fundamental questions, with groundbreaking discoveries emerging from research carried out in Uruguay. Powered by technological advances, the field has seen milestones in ultrastructure, neuronal and synaptic structure, and complex behavioral findings. Key contributions include the first formal description of chemical synapses, the identification of synaptic vesicle origins in the endoplasmic reticulum, and pioneering work on eye induction and development.
View Article and Find Full Text PDFClarity unveiled: A journey through time in cataract surgery.
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University of Derby, Derby, UK.
This historical research article offers a comprehensive examination of the evolution of cataract surgery from ancient practices to modern innovations. The historical trajectory of cataract treatment will be explored, beginning with ancient techniques such as couching in ancient civilisations and progressing through critical milestones in surgical advancement. The research delves into the challenges faced by early practitioners, the emergence of novel techniques and the pivotal contributions of pioneering surgeons throughout history.
View Article and Find Full Text PDFA Brief History of Cell Culture: From Harrison to Organs-on-a-Chip.
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Department of Genetic, Ribeirão Preto Medical School, University of São Paulo-USP, Ribeirão Preto 14040-904, Brazil.
This comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux's seminal experiments in the 1880s, followed by the pioneering efforts of Ross Granville Harrison, who initiated groundbreaking experiments that fundamentally shaped the landscape of cell culture in the early 20th century. Carrel's influential contributions, notably the immortalization of chicken heart cells, have marked a significant advancement in cell culture techniques.
View Article and Find Full Text PDFWorkshop report: Clinical training and integration of genetic counselors into interprofessional teams in the German-speaking countries.
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Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
In spring 2022, the inaugural cohort of Genetic and Genomic Counseling MSc students graduated from the Medical University of Innsbruck, representing a significant milestone for the establishment of the genetic counselor (GC) profession in the German-speaking countries. A pivotal component of their education was a 15-week clinical training period. The placement experiences of both students and supervisors offered valuable insights into the attitudes of medical geneticists toward the profession.
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Sorbonne Université, CNRS, Institut de Biologie Physico-Chimique, Laboratoire de Biologie Moléculaire et Cellulaire des Eucaryotes, LBMCE, F-75005 Paris, France
, a model organism in telomere biology, has been instrumental in pioneering a comprehensive understanding of the molecular processes that occur in the absence of telomerase across eukaryotes. This exploration spans investigations into telomere dynamics, intracellular signaling cascades, and organelle-mediated responses, elucidating their impact on proliferative capacity, genome stability, and cellular variability. Through the lens of budding yeast, numerous sources of cellular heterogeneity have been identified, dissected, and modeled, shedding light on the risks associated with telomeric state transitions, including the evasion of senescence.
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