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Synthesis of (R)-(+)-hippospongic acid A, a triterpene isolated from the marine sponge, Hippospongia sp. | LitMetric
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Synthesis of (R)-(+)-hippospongic acid A, a triterpene isolated from the marine sponge, Hippospongia sp.

M Ichihashi H Takikawa K Mori

Biosci Biotechnol Biochem

Department of Chemistry, Science University of Tokyo, Japan.

Published: November 2001

Hippospongic acid A (1) is a triterpene metabolite of the marine sponge, Hippospongia sp., with inhibitory activity against the gastrulation of starfish embryos. (R)-(+)-1 was synthesized by employing enzymatic kinetic resolution as the key step.

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http://dx.doi.org/10.1271/bbb.65.2569DOI Listing

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