Purpose: The authors studied the utility of Ga-67 citrate scintigraphy in patients with breast lymphoma.
Methods: Seven patients with histologically proved breast lymphoma were examined. In three patients, both breasts were involved, and all patients had rapidly growing breast masses. Planar and SPECT images were obtained 72 hours after injection of Ga-67.
Results: Ga-67 scintigraphy showed intense accumulation in all lymphomas. SPECT images provided better contrast than did planar images. In one of the seven patients, the axilla and mediastinum were also involved. In six of the seven patients, Ga-67 scintigraphy was also performed after treatment and showed the disappearance of Ga-67 accumulation. In one patient with local recurrence and lung involvement, abnormal accumulation was depicted on follow-up Ga-67 scintigraphy.
Conclusions: Ga-67 scintigraphy was helpful to confirm the diagnosis and the systemic extent of lymphoma and to evaluate the therapeutic effect during follow-up in patients with breast lymphoma.
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http://dx.doi.org/10.1097/00003072-200202000-00005 | DOI Listing |
J Infect Dis
October 2023
Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
For nearly 50 years, nuclear medicine has played an important role in the diagnosis of infection. Gallium citrate Ga 67 was one of the first, if not the first, radionuclide used for this purpose. Unfavorable imaging characteristics, a lack of specificity, and the long interval (2-3 days) between administration and imaging spurred the search for alternatives.
View Article and Find Full Text PDFF1000Res
September 2023
Department of Nephrology, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
Immunoglobulin G4 (IgG4)-related disease is a systemic inflammatory disorder characterized by tubulointerstitial nephritis with IgG4-positive plasma cell infiltration. We report the case of an 84-year-old male who presented with a history of dyspnea on exertion and cough. The lymph nodes were palpated in the axilla.
View Article and Find Full Text PDFIndian J Nucl Med
November 2022
Department of Nuclear Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Bone infections are a common problem, and early diagnosis and intervention can lead to better clinical outcomes and prognoses. Here, we compare the well-known tracers Gallium-67 (Ga-67) citrate versus Ga-68 citrate in the diagnosis of infections.
View Article and Find Full Text PDFInt J Mol Sci
November 2022
Molecular Radiopharmacy, INRaSTES, NCSR "Demokritos", GR-15310 Athens, Greece.
Radiolabeled somatostatin subtype 2 receptor (SST2R)-antagonists have shown advantageous profiles for cancer theranostics compared with agonists. On the other hand, the newly introduced hybrid chelator (6-pentanoic acid)-6-(amino)methyl-1,4-diazepinetriacetate (DATA) rapidly binds Ga-68 (t: 67.7 min) at much lower temperature, thus allowing for quick access to "ready-for-injection" [Ga]Ga-tracers in hospitals.
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