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Atrial Fibrillation Related Titin Truncation Is Associated With Atrial Myopathy in Patient-Derived Induced Pluripotent Stem Cell Disease Models.
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Centre for Heart Lung Innovation, University of British Columbia, Vancouver. (K.H., M.A., L.R., Y.L., A.S., H.H., L.R.B., Z.W.L.).
Background: Protein-truncating mutations in the titin gene are associated with increased risk of atrial fibrillation. However, little is known about the underlying pathophysiology.
Methods: We identified a heterozygous titin truncating variant (TTNtv) in a patient with unexplained early onset atrial fibrillation and normal ventricular function.
The economic burden of atopic dermatitis in Romania: a broad perspective.
Front Public Health
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Dermatology Department, Colentina Clinical Hospital, Bucharest, Romania.
Introduction: Atopic dermatitis (AD), a common dermatological condition, is often associated with significant economic and social burdens. Despite extensive studies globally, there is a gap in understanding the impact of this condition in Romania. This study evaluated the economic burden of AD in Romania, considering both direct and indirect costs.
View Article and Find Full Text PDFIntegrated health and nutrition approaches to school feeding: maximising future human capital in Latin America and the Caribbean.
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Social Protection and Nutrition Unit, Programme Division, World Food Programme, Panama City, Panama.
Integrated health and nutrition packages in schools have been shown to be a cost-effective approach to support children's well-being and academic achievement; yet few countries adequately invest in promoting such integration. School feeding programmes in Latin America are among the best-established, with some of the largest scale and coverage in the world. National School Meal programmes in Latin America and the Caribbean benefit over 80.
View Article and Find Full Text PDFCross-cultural validation and reference norms for the DCDDaily-Q questionnaire Chinese version (DCDDaily-Q-CN): evaluating children's motor performance in activities of daily living.
Front Public Health
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Department of Rehabilitation Medicine, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
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View Article and Find Full Text PDFThe effectiveness of non-invasive brain stimulation in enhancing lower extremity function in children with spastic cerebral palsy: Protocol for a systematic review and meta-analysis.
MethodsX
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Faculty of Nursing and Physiotherapy, Universidad de Lleida, Roig 2, 25198 Lleida, Montserrat, España.
Non-invasive brain stimulation (NIBS) techniques have emerged as a promising non-pharmacological adjunct to neurorehabilitation. Children with Cerebral Palsy (CP) exhibit altered cortical excitability, and while CP remains incurable, physiotherapy combined with other interventions is essential for managing motor dysfunction. Although some studies have examined NIBS using various stimulation parameters, there is limited evidence regarding its effects on the lower extremities and optimal administration protocols.
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