AI Article Synopsis
- RNA-mediated genetic interference (RNAi) is a key tool for studying gene function in various biological processes, including development.
- RNAi can enhance traditional genetic studies or serve as the main approach to understanding biological functions.
- The review specifically looks at germline development in C. elegans, highlighting both the advantages and limitations of RNAi and its potential roles in germline physiology.
Article Abstract
RNA-mediated genetic interference (RNAi) has become a very useful tool for analyzing gene function in development and other processes. RNAi can be used as a complement to traditional genetic studies or as a primary means of determining biological function. However, the efficacy of RNAi depends on a variety of factors that the researcher must take into consideration. This review focuses on germline development in the nematode, Caenorhabditis elegans, and discusses the uses and limitations of RNAi in providing new information about gene function as well as the possible endogenous role RNAi plays in germline physiology.
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| http://dx.doi.org/10.1006/dbio.2001.0394 | DOI Listing |
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