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Thyroid dysfunction in women with a menopausal syndrome.
Prz Menopauzalny
September 2024
Department of Internal Medicine No1, Odesa National Medical University, Odesa, Ukraine.
Introduction: The thyroid gland has a significant impact on the morphofunctional state of the organs of the female reproductive system, the regulation of the ovarian-menstrual cycle, as well as the age-related decline of the generative and endocrine function of the ovaries.
Material And Methods: The study involved 102 women aged 49-62 years, who were divided into 2 groups. Group I included 54 patients who suffered from manifestations of the menopausal syndrome, and the control group comprised 48 patients whose menopausal period proceeded physiologically.
Amniotic Fluid Embolism in a Patient Presenting for Induction of Labor for Cholestasis of Pregnancy.
Cureus
August 2024
Anesthesiology, Mountain West Anesthesia, Lehi, USA.
Article Synopsis
- * A 28-year-old woman with multiple health issues was induced for labor but suffered a sudden cardiac arrest, necessitating an emergency cesarean section.
- * Following the event, the patient faced complications such as coagulopathy and uterine atony, leading to a hysterectomy and supportive treatment before being stabilized for transport to a specialized care facility.
The correlation of lipid profile with subclinical and overt hypothyroidism: A cross-sectional study from Syria.
Medicine (Baltimore)
September 2023
Prof. Department of Endocrinology, Damascus University - Faculty of Medicine, Damascus, Syria.
We proceeded with this study to investigate the relationship between hypothyroidism and lipid profile disturbance. A cross-sectional study at Al- Mowasat University Hospital in Damascus was conducted from March 2021 to March 2022, and included 324 adults. For each participant with abnormal thyroid stimulating hormone (TSH), free thyroxine (FT4) was requested.
View Article and Find Full Text PDFTreatment- and immune-related adverse events of immune checkpoint inhibitors in esophageal or gastroesophageal junction cancer: A network meta-analysis of randomized controlled trials.
Front Oncol
December 2022
Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Objective: To systematically evaluate the safety and adverse event profiles of immune checkpoint inhibitors (ICIs) in patients with esophageal cancer (EPC) or gastroesophageal junction cancer (GEJC).
Methods: PubMed, Web of Science, Cochrane Library, and major conference proceedings were systematically searched for all phase II or phase III randomized controlled trials (RCTs) in EPC or GEJC using ICIs. Safety outcomes including treatment-related adverse events (trAEs), immune-related adverse events (irAEs), and serious trAEs were evaluated by network meta-analysis or dichotomous meta-analysis based on the random-effects model.
Toxicity profile of combined immune checkpoint inhibitors and thoracic radiotherapy in esophageal cancer: A meta-analysis and systematic review.
Front Immunol
November 2022
Department of Radiotherapy Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Background: Therapies based on the combination of immune checkpoint inhibitors (ICIs) and thoracic radiotherapy (TRT) are transforming the treatment landscape of esophageal cancer. Nevertheless, the available data on adverse events (AEs) mainly stemmed from several prospective clinical trials and retrospective studies, in which, AE data are often handled and reported with less rigor than the primary beneficial outcomes of the study. Thus, we conducted a systematic review to investigate the toxicity spectrum of these novel regimens.
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