Why is p53 acetylated?

Cell

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Published: December 2001

Recent studies suggest that acetylation of the p53 tumor suppressor protein is not important for its DNA binding activity, as was previously thought. We discuss here a number of theories as to how this modification may serve to regulate the protein's functions.

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Source
http://dx.doi.org/10.1016/s0092-8674(01)00619-5DOI Listing

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