[Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp].

Zhonghua Kou Qiang Yi Xue Za Zhi

School of Stomatology, China Medical University, Shenyang 110002.

Published: July 1999

Objective: To study the change of the levels of 6-keto-prostaglandin F1 alpha (6-K-PGF1 alpha) and thromboxane B2 (TXB2) in deep caries and pulpitis pulp.

Methods: The levels of 6-K-PGF1 alpha and TXB2 were determined by radioimmunoassay (RIA) in 44 pulp tissues from subjects with healthy pulp (H), deep caries (DC), chronic pulpitis (CP) and acute pulpitis(AP). The 6-K-PGF1 alpha/TXB2 ratio(K/T) was calculated.

Results: The lconcentrations of 6-K-PGF1 alpha in Group AP were highest and those in Group H were lowest. The levels of TXB2 in Group DC were lower than Group CP and those in Group H were lowest. Significant differences in K/T ratio were found among the groups except those between Group H and DC. The value of Group AP was highest and that of Group CP was lowest.

Conclusion: The dysbolism and dysequilibrium of PGI2 and TXA2 may be closely related to the genesis of pulp diseases.

Download full-text PDF

Source

Publication Analysis

Top Keywords

6-k-pgf1 alpha
12
6-keto-prostaglandin alpha
8
alpha thromboxane
8
deep caries
8
group
8
group highest
8
highest group
8
group lowest
8
group group
8
alpha
5

Similar Publications

Objective: To investigate the effect and hemostatic mechanism of Shenqi Guchong Recipe (SGR) in treating peri-menopausal anovulatory dysfunctional uterine bleeding (ADUB) of qi deficiency blood stasis syndrome type (QDBS).

Methods: Patients of ADUB-QDBS were assigned to two groups, the 47 patients in the treated group administering orally with SGR and the 31 in the control group treated with Kunning Oral Liquid. The hemostatic effect, and the changes before and after treatment of 6-ketoprostaglandin 1alpha (6-K-PGF1 alpha), thromboxane B2(TXB2), T-lymphocyte subsets (CD3 and CD8, CD4/CD8 ratio) in menstrual blood, and serum calcium level in patients were observed.

View Article and Find Full Text PDF

To observe the effects of silkworm pupa oil on serum lipids level and platelet function in rats, according to serum TG, TC level, 40 male Wistar rats are divided into four groups (normal control group, high fat control group, silkworm pupa oil group and silkworm pupa oil + VE group). The rats are fed different diets and six weeks later, serum lipids level and platelet function are measured. The results show that (1) Compared with high fat control group, serum TC, TG, LDL-C level, AI value, Platelet aggregability, plasma TXB2 level and T/P ratio decrease significantly while HDL-C level and 6-k-PGF1 level increase in silkworm pupa oil group; (2) Serum TC, LDL-C level, T/P ratio and platelet aggregability are significantly lower in silkworm pupa oil + VE group than in silkworm pupa oil group.

View Article and Find Full Text PDF

[Clinical study on conducting physical exercise in lowering blood pressure of hypertensive patients and influencing their endocrine hormones].

Zhongguo Zhong Xi Yi Jie He Za Zhi

December 2001

Zhejiang Academy of Traditional Chinese Medicine, Hangzhou 310007.

Objective: To explore the mechanism of conducting physical exercise to lower blood pressure of hypertensive patients, relieve their symptoms and influence the cardiovascular endocrine hormone.

Methods: One hundred and twenty-five patients with II or III stage hypertension were divided into the experimental group and the control group and observed. The comparison of conditions before and after treatment, and between experimental and control groups was carried out.

View Article and Find Full Text PDF

[Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp].

Zhonghua Kou Qiang Yi Xue Za Zhi

July 1999

School of Stomatology, China Medical University, Shenyang 110002.

Objective: To study the change of the levels of 6-keto-prostaglandin F1 alpha (6-K-PGF1 alpha) and thromboxane B2 (TXB2) in deep caries and pulpitis pulp.

Methods: The levels of 6-K-PGF1 alpha and TXB2 were determined by radioimmunoassay (RIA) in 44 pulp tissues from subjects with healthy pulp (H), deep caries (DC), chronic pulpitis (CP) and acute pulpitis(AP). The 6-K-PGF1 alpha/TXB2 ratio(K/T) was calculated.

View Article and Find Full Text PDF

The role of prostacyclin (PGI2) and thromboxane A2 (TXA2) in pathogenesis of dengue hemorrhagic fever (DHF).

J Med Assoc Thai

November 1999

Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

In previous studies it has been demonstrated that the levels of plasma 6 keto-prostaglandin F1 alpha (6-K-PGF1), the stable metabolite of PGI2 were elevated in DHF patients during shock. In this study it is hypothesized that excessive PGI2 production plays a very important role in developing serious clinical manifestations of dengue shock syndrome (DSS) patients. In addition, an attempt was made to determine whether TXA2 has any significant role in such patients.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!