AI Article Synopsis
- A study measured thrombin generation in 59 patients with unstable angina during unstable and stable periods, comparing results to 31 healthy controls.
- Thrombin generation was significantly higher during the unstable period compared to both the healthy controls at rest and the stable period in patients (p < 0.0001).
- The variations in thrombin generation were linked to how long the patients had been experiencing unstable angina, rather than the improvement in the severity of their coronary artery blockages.
Article Abstract
Platelet-dependent thrombin generation was assessed during both unstable and stable periods in 59 patients with unstable angina and at rest in 31 healthy controls. Thrombin generation during the unstable period was significantly greater than that at rest in the healthy control group (p < 0.0001) and that during the stable period (p < 0.0001). Changes in thrombin generation were related to the time after onset of unstable angina, not to degree of improvement in the severity of coronary stenosis.
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| http://dx.doi.org/10.1177/000331970105201202 | DOI Listing |
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