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Alzheimers Dement
December 2024
Indiana University School of Medicine, Department of Psychiatry, Indianapolis, IN, USA.
Background: Major contributors to AD pathogenesis include aggregates of amyloid-β (Aβ) peptides, hyperphosphorylated tau protein, and neuroinflammation. No currently approved treatment stops or significantly slows the progression of AD. Nevertheless, one class of agents that has shown promise is metal chelators.
View Article and Find Full Text PDF[O-arm Versus C-arm: Comparison of the Learning Curves and Accuracy in Transpedicular Screw Fixation of Lumbar Spondylolisthesis].
Acta Chir Orthop Traumatol Cech
January 2025
Neurochirurgická klinika Fakultní nemocnice Olomouc.
Purpose Of The Study: The annual number of spinal fusion procedures has been increasing and is well documented worldwide. The O-arm is slowly becoming the standard for transpedicular screw insertion. The accuracy and safety of this method have been confirmed by many studies.
View Article and Find Full Text PDF[Screw Angle and Condylar Ratio as Possible Parameters to Monitor the Treatment of Idiopathic Axial lower Limb Deformities Using Eight-Figure Plates].
Acta Chir Orthop Traumatol Cech
January 2025
Klinika dětské chirurgie, ortopedie a traumatologie Fakultní nemocnice Brno.
Purpose Of The Study: Temporary hemiepiphyseodesis using figure-eight plates is currently one of the main surgical techniques to correct axial deformities of lower limbs in paediatric patients. Comprehensive analysis, correct indication and monitoring of treatment are the basic prerequisites for successful therapy. The aim of the study was to analyse parameters that could become an alternative to standard parameters used nowadays, namely the inserted screw angle (SA), and a new parameter - condylar ratio (CR).
View Article and Find Full Text PDFOutcomes of Unrestricted Weight-Bearing During Interval Period With Cement-on-Cement Articulating Antibiotic-Loaded Spacers in Two-Stage Revision for Knee Prosthetic Joint Infection.
Cureus
December 2024
Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, JPN.
Background: Two-stage revision is known as the gold-standard method for knee prosthetic joint infection (PJI), but the most suitable treatment method remains controversial. Typically, weight-bearing is restricted during the interval between the stages. The aim of this study was to evaluate the clinical outcomes of unrestricted weight bearing with cement spacers fabricated using the Knee Articulating Spacer Mold (KASM®; Ortho Development Corporation, Draper, UT, USA) for knee PJI.
View Article and Find Full Text PDFFBG-based Shape-Sensing to Enable Lateral Deflection Methods of Autonomous Needle Insertion.
Rep U S
October 2024
Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.
In diagnosing and treating prostate cancer the flexible bevel tip needle insertion surgical technique is commonly used. Bevel tip needles experience asymmetric loading on the needle's tip, inducing natural bending of the needle and enabling control mechanisms for precise placement of the needle during surgery. Several methods leverage the needles natural bending to provide autonomous control of needle insertion for accurate needle placement in an effort to reduce excess tissue damage and improve patient outcomes from needle insertion intraventions.
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