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Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment. | LitMetric
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Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment.

Anthony P Shuber Jennifer J Ascaño Kevin A Boynton Anastasia Mitchell Henry F Frierson Wa'el El-Rifai Steven M Powell

J Clin Microbiol

Applied Research Group, Exact Sciences Corporation, Maynard, Massachusetts 01754, USA.

Published: January 2002

A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC120120PMC
http://dx.doi.org/10.1128/JCM.40.1.262-264.2002DOI Listing

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