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Article Synopsis
  • The case report discusses a unique instance of endometrial carcinosarcoma, a rare and aggressive tumor, detailing its clinical signs, MRI characteristics, and surgical treatment.
  • It emphasizes the importance of multimodal MRI techniques, including T1WI and T2WI, in accurately identifying the tumor’s features and guiding preoperative planning.
  • The report concludes that multimodal MRI enhances diagnostic accuracy and aids in differentiating carcinosarcoma from other types of endometrial cancer, particularly when combined with specific biomarkers.
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Background: Pulmonary sarcomatoid carcinoma (PSC) is a rare lung cancer characterized by early metastasis and invasion. It is predominantly diagnosed at a locally advanced or metastatic stage, hindering the possibility of surgical intervention. However, a standard treatment for advanced PSC remains unestablished.

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Sarcomatoid carcinoma of small intestine.

BMJ Case Rep

January 2025

Department of Pathology, New York Medical College, Valhalla, New York, USA

Sarcomatoid carcinoma is a rare type of tumour consisting of neoplastic cells expressing both epithelial and mesenchymal cell markers. The small intestine is a rare site for sarcomatoid carcinoma and to date, a few cases have been reported. In this manuscript, a case of jejunal sarcomatoid carcinoma in a man in his 50s is reported.

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Background: Black women with epithelial ovarian cancer (EOC) have worse survival and a higher burden of comorbid conditions compared with other racial groups. This study examines the association of comorbid conditions and medication use for these conditions with survival among Black women with EOC.

Methods: In a prospective study of 592 Black women with EOC, the Charlson comorbidity index (CCI) based on self-reported data, three cardiometabolic comorbidities (type 2 diabetes, hypertension, and hyperlipidemia), and medication use for each cardiometabolic comorbidity were evaluated.

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Background: Although rare, uterine sarcomas account for a high proportion of uterine cancer mortality. Treatment options and robust trial data are limited.

Objectives: The TOURISM study (Treatment Outcomes in UteRIne SarcoMa) is a UK-wide study by the National Oncology Trainees Collaborative for Healthcare Research which aimed to characterise this patient cohort.

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