The US Lab module of the International Space Station (ISS) is a primary working area where the crewmembers are expected to spend majority of their time. Because of the directionality of radiation fields caused by the Earth shadow, trapped radiation pitch angle distribution, and inherent variations in the ISS shielding, a model is needed to account for these local variations in the radiation distribution. We present the calculated radiation dose (rem/yr) values for over 3,000 different points in the working area of the Lab module and estimated radiation dose values for over 25,000 different points in the human body for a given ambient radiation environment. These estimated radiation dose values are presented in a three dimensional animated interactive visualization format. Such interactive animated visualization of the radiation distribution can be generated in near real-time to track changes in the radiation environment during the orbit precession of the ISS.
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Free Radic Res
January 2025
Radiation Biology & Health Sciences Division, Bio-science Group, Bhabha Atomic Research Centre, Trombay, Mumbai-400085, India.
Free radicals have been implicated in the pathogenesis of cancer along with cardiovascular, neurodegenerative, pulmonary and inflammatory disorders. Further, the relationship between oxidative stress and disease is distinctively established. Clinical trials using anti-oxidants for the prevention of disease progression have indicated some beneficial effects.
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August 2024
Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.
The escalating global threat of climate change is becoming more evident. The climate crisis intersects with another major challenge: lung cancer. With Asia already bearing half the global cancer burden, the impact of climate-related events on health and on lung cancer care specifically are profound.
View Article and Find Full Text PDFPhys Med Biol
January 2025
Radiation Oncology, Amsterdam UMC Location AMC, Meibergdreef 9, Amsterdam, Noord-Holland, 1105 AZ, NETHERLANDS.
Conventional temperature optimisation in Hyperthermia Treatment Planning aims to maximise tumour temperature (e.g., T90; the temperature reached in at least 90% of the tumour) while enforcing hard constraints on normal tissue temperature (max(Ttissue)≤45°C).
View Article and Find Full Text PDFHealth Phys
January 2025
Department of Radiation Oncology, Medicine Faculty of Van Yüzüncü Yıl University, Van, Turkey.
Quality assurance practices performed before treatment are believed to identify various potential errors. In this study, 2-dimensional (2D) dosimetric results were analyzed by making some intentional mistakes in six different treatment plans. In this way, the detectability of errors was investigated.
View Article and Find Full Text PDFRev Sci Instrum
January 2025
School of Electronic and Information Engineering, Nanjing University of Information Science and Technology, Nanjing 210000, China.
Aiming at the effects caused by stress and deformation on Micro-Electro-Mechanical System (MEMS) sensors, the stress distribution in the radiation area of the MEMS infrared light source is investigated, and by simulating and optimizing the thickness of the composite support film of the chip structure in COMSOL, a film layer thickness matching with lower stress and deformation for the MEMS infrared light source is derived. The utilization of the particle swarm algorithm and backpropagation neural network model allowed for the optimization of simulation data, enabling regression prediction over a broader range of thicknesses and providing a more precise depiction of the stress distribution trend. In addition, the specifications of the MEMS device help us to analyze the design of the support film thickness in the processing of the residual stress within the controllable range.
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