Alternatives to animal testing in microbiology and infectiology.

Contrib Microbiol

FRAME-Fund for the Replacement of Animals in Medical Experiments, Nottingham, UK.

Published: May 2002

Download full-text PDF

Source
http://dx.doi.org/10.1159/000060391DOI Listing

Publication Analysis

Top Keywords

alternatives animal
4
animal testing
4
testing microbiology
4
microbiology infectiology
4
alternatives
1
testing
1
microbiology
1
infectiology
1

Similar Publications

Predicting the spatial and temporal responses of species exhibiting intraguild predation (IGP) relationships is difficult due to variation in potential interactions and environmental context. Eurasian badgers () are intraguild predators of European hedgehogs () and are implicated in their population decline via both direct predation and competition for shared food resources. Previous studies have shown spatial separation between these species and attributed this to hedgehogs experiencing a 'landscape of fear', but little is known about the potential role of differential habitat use.

View Article and Find Full Text PDF

Cellular senescence induced by down-regulation of correlates with exon skipping of mitochondrial-related gene .

Life Med

April 2024

Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, School of Life Sciences, Fudan University, Shanghai 200438, China.

As the most prevalent type of alternative splicing in animal cells, exon skipping plays an important role in expanding the diversity of transcriptome and proteome, thereby participating in the regulation of diverse physiological and pathological processes such as development, aging, and cancer. Cellular senescence serving as an anti-cancer mechanism could also contribute to individual aging. Although the dynamic changes of exon skipping during cellular senescence were revealed, its biological consequence and upstream regulator remain poorly understood.

View Article and Find Full Text PDF

Effects of partial replacement of soybean meal with and lysozyme on diarrheal incidence, plasma biochemical parameters, and immunity of weaned piglets.

Front Vet Sci

January 2025

CAS Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, China.

Introduction: The study aimed to investigate the effects of and lysozyme on growth performance, diarrhea rate, immune function, plasma biochemical parameters, and gut microbiota and metabolites of weaned piglets.

Methods: Thirty weaned Xiangcun black piglets (BW, 11.47 ± 1.

View Article and Find Full Text PDF

Introduction: Hyperthermia is an established adjunct in multimodal cancer treatments, with mechanisms including cell death, immune modulation, and vascular changes. Traditional hyperthermia applications are resource-intensive and often associated with patient morbidity, limiting their clinical accessibility. Gold nanorods (GNRs) offer a precise, minimally invasive alternative by leveraging near-infrared (NIR) light to deliver targeted hyperthermia therapy (THT).

View Article and Find Full Text PDF

Alternate day fasting aggravates atherosclerosis through the suppression of hepatic ATF3 in mice.

Life Metab

June 2024

Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.

Atherosclerosis is the major contributor to cardiovascular mortality worldwide. Alternate day fasting (ADF) has gained growing attention due to its metabolic benefits. However, the effects of ADF on atherosclerotic plaque formation remain inconsistent and controversial in atherosclerotic animal models.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!