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Blood Trihalomethanes and Human Cancer: A Systematic Review and Meta-Analysis.
Toxics
January 2025
School of Public Health, MOE Key Laboratory of Geriatric Diseases and Immunology Suzhou Medical College, Soochow University, Suzhou 215123, China.
The control of waterborne diseases through water disinfection is a significant advancement in public health. However, the disinfection process generates disinfection by-products (DBPs), including trihalomethanes (THMs), which are considered to influence the occurrence of cancer. This analysis aims to quantitatively evaluate the relationship between blood concentrations of THMs and cancer.
View Article and Find Full Text PDFSafety, Immunogenicity, and Efficacy of Cytomegalovirus Vaccines: A Systematic Review of Randomized Controlled Trials.
Vaccines (Basel)
January 2025
Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, 60126 Ancona, Italy.
Cytomegalovirus (CMV) is widespread and mostly causes asymptomatic infections in immunocompetent hosts, but it may lead to severe and life-threatening diseases in immunocompromised individuals, such as transplant patients and congenitally infected children, representing a significant public health concern. Although there are no licensed CMV vaccines, the development of a CMV vaccine is considered a high priority due to its potential to reduce the burden associated with CMV-related complications, and several approaches are under investigation. The objective of this systematic review was to synthesize the evidence on various CMV vaccines currently under clinical development.
View Article and Find Full Text PDFFoodborne Infections and : Current Primary Prevention Tools and Future Perspectives.
Vaccines (Basel)
December 2024
Food Hygiene and Nutrition Service, Local Health Unit 3, Department of Prevention, 16142 Genoa, Italy.
is considered the major zoonotic and foodborne pathogen responsible for human infections. It includes the serovars causing typhoid fever ( and ) and the non-typhoidal salmonella (NTS) serovars ( and ), causing enteric infections known as "Salmonellosis". NTS represents a major public health burden worldwide.
View Article and Find Full Text PDFImpact of Periodontitis and Oral Dysbiosis Metabolites in the Modulation of Accelerating Ageing and Human Senescence.
Metabolites
January 2025
Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.
Periodontitis, a chronic multifactorial inflammatory condition of the periodontium, is originated by a dysbiotic oral microbiota and is negatively correlated with several systemic diseases. The low-chronic burden of gingival inflammation not only exacerbates periodontitis but also predisposes individuals to a spectrum of age-related conditions, including cardiovascular diseases, neurodegenerative disorders, and metabolic dysfunction, especially related to ageing. In this regard, over the local periodontal treatment, lifestyle modifications and adjunctive therapies may offer synergistic benefits in ameliorating both oral and systemic health in ageing populations.
View Article and Find Full Text PDFClear Aligner Treatment: Indications, Advantages, and Adverse Effects-A Systematic Review.
Dent J (Basel)
January 2025
Section of Orthodontics, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages, and adverse effects in CAT. : A search was performed in the PubMed and Embase databases, yielding 18 studies eligible for inclusion.
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